Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509418 | 1.00 | SOS2 (0.71) | SOS2HTR2ASCN9AMAPTSMN1; SMN2 | |
| SCHEMBL5151098 | 1.00 | SOS2 (0.71) | SOS2HTR2ASCN9AMAPTSMN1; SMN2 | |
| SCHEMBL26617451 | 0.87 | SOS2 (0.73) | SOS2HTR2ASCN9AMAPTSMN1; SMN2 | |
| SCHEMBL10646800 | 0.83 | SOS2 (1.00) | SOS2HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL10182315 | 0.83 | SOS2 (1.00) | SOS2HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL10183456 | 0.83 | SOS2 (1.00) | SOS2HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL18156572 | 0.82 | HTR2A (0.57) | SOS2HTR2ASCN9APCSK9NR4A2 | |
| SCHEMBL10023253 | 0.80 | SOS2 (0.68) | SOS2HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL18509675 | 0.80 | SCN9A (0.80) | SOS2HTR2ASCN9AMAPTADRB1 | |
| SCHEMBL2033276 | 0.80 | SOS2 (0.68) | SOS2HTR2AMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | SOS2 4597/4885HTR2A 11/4885SCN9A 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.