Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | UBE2N | P61088 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | CNR2 | P34972 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551931 | 0.85 | MAPK1 (0.55) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL29165483 | 0.82 | MAPK1 (0.58) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL11122826 | 0.76 | MAPK1 (0.41) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL29757970 | 0.75 | MAPK1 (0.43) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL1241939 | 0.75 | MAPK1 (0.40) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL29630093 | 0.75 | MAPK1 (0.47) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL778350 | 0.75 | MAPK1 (0.47) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL2071016 | 0.74 | MAPK1 (0.43) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL228138 | 0.74 | ALDH1A1 (0.53) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 | |
| SCHEMBL187755 | 0.74 | NPC1 (1.00) | MAPK1SMN1; SMN2RAB9ANPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173614-A1 | Polyether composition | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1737913-A1 | POLYETHER COMPOSITION | Nippon Shokubai Co.,Ltd. (JP) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005085354-A1 | POLYETHER COMPOSITION | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173614-A1 | Polyether composition | PUF60, RPL37A, RPL30 | MAPK1 3523/4885SMN1; SMN2 713/4885RAB9A 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.