Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237432 | 0.93 | HRH3 (0.50) | HRH3HRH4F2HPGDPARP1 | |
| Trifluoroacetic Acid SCHEMBL5150811 | 0.83 | GRB2 (0.44) | GRB2DPP4F2HPGDPTPN1 | |
| Trifluoroacetic Acid SCHEMBL5151176 | 0.81 | GRB2 (0.42) | HTR5AGRB2DPP4F2HPGD | |
| Trifluoroacetic Acid SCHEMBL5155526 | 0.81 | GRB2 (0.42) | HRH3GRB2DPP4HPGDPTPN1 | |
| Trifluoroacetic Acid SCHEMBL5148861 | 0.77 | KCNH2 (0.41) | HRH3DPP4DPP8DPP7 | |
| SCHEMBL5233793 | 0.75 | CACNA1B (0.50) | HRH3HRH4PTPN1 | |
| SCHEMBL5234301 | 0.74 | HDAC1 (0.48) | F2HPGDMC4RMC5RMC3R | |
| SCHEMBL5232357 | 0.74 | HPGD (0.38) | GRB2F2HPGDACACBMC4R | |
| Trifluoroacetic Acid SCHEMBL5151174 | 0.73 | GRB2 (0.40) | HTR5AGRB2F2PTPN1 | |
| SCHEMBL27537681 | 0.73 | CHRM2 (0.41) | HRH3DPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |