Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 9/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5151636 | 0.93 | HRH3 (0.44) | HRH3HRH4PARP1ACACBF2 | |
| SCHEMBL5234301 | 0.80 | HDAC1 (0.48) | F2MC4RMC5RMC3RHPGD | |
| SCHEMBL27537681 | 0.78 | CHRM2 (0.41) | HRH3MC4RMC5RMC3R | |
| SCHEMBL5154437 | 0.78 | HDAC8 (0.43) | HRH3F2MC4RMC5RMC3R | |
| SCHEMBL5232357 | 0.76 | HPGD (0.38) | ACACBF2MC4RMC5RMC3R | |
| SCHEMBL5233793 | 0.76 | CACNA1B (0.50) | HRH3HRH4 | |
| SCHEMBL5236489 | 0.73 | ACACB (0.49) | HRH3HRH4ACACB | |
| Trifluoroacetic Acid SCHEMBL5150811 | 0.73 | GRB2 (0.44) | F2MC4RMC5RMC3RHPGD | |
| SCHEMBL5234435 | 0.73 | HRH3 (0.45) | HRH3ACACB | |
| Hydrochloric Acid SCHEMBL5151770 | 0.72 | ACACB (0.48) | HRH3HRH4ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |
| CN-1297546-C | N- (arylsulfonyl) -beta-amino acid derivatives with substituted aminomethyl group, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2007-01-31 | — | — | CN | disclosed |
| CN-1541211-A | Derivatives of N-(arylsulfonyl) beta-aminoacids comprising substituted aminomethyl group, prepn. method thereof and pharmaceutical compsns. contg same | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-10-27 | — | — | CN | disclosed |
| EP-1373233-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076964-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-10-03 | — | — | WO | disclosed |