Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879329 | 0.83 | DPP4 (0.40) | KMT2ADPP4DPP7DPP8DPP9 | |
| SCHEMBL27559390 | 0.82 | SLC7A5 (0.50) | CHRM2KMT2ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL5236489 | 0.79 | ACACB (0.49) | OPRK1HRH3ALDH1A1KDM4EOPRM1 | |
| SCHEMBL5234435 | 0.79 | HRH3 (0.45) | CHRM2HRH3KMT2AALDH1A1KDM4E | |
| SCHEMBL5237432 | 0.78 | HRH3 (0.50) | HRH3MC4RMC5RMC3R | |
| Hydrochloric Acid SCHEMBL5151770 | 0.78 | ACACB (0.48) | OPRK1HRH3ALDH1A1KDM4EOPRM1 | |
| Trifluoroacetic Acid SCHEMBL5148861 | 0.73 | KCNH2 (0.41) | GPR119HRH3KMT2ADPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL5151636 | 0.73 | HRH3 (0.44) | HRH3MC4RMC5RMC3RDPP4 | |
| SCHEMBL5234301 | 0.72 | HDAC1 (0.48) | CHRM2MC4RMC5RMC3RKMT2A | |
| SCHEMBL14542190 | 0.72 | ALDH1A1 (0.44) | OPRK1KMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1297546-C | N- (arylsulfonyl) -beta-amino acid derivatives with substituted aminomethyl group, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2007-01-31 | — | — | CN | disclosed |
| CN-1541211-A | Derivatives of N-(arylsulfonyl) beta-aminoacids comprising substituted aminomethyl group, prepn. method thereof and pharmaceutical compsns. contg same | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-10-27 | — | — | CN | disclosed |