SCHEMBL515196

SCHEMBL515196

C=CCOc1ccccc1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 4/20 0.59
ADRB1 P08588 2/20 0.59
MAPK1 P28482 2/20 0.53
TP53 P04637 1/20 0.53
RAB9A P51151 1/20 0.53
HTT P42858 1/20 0.52
HTR7 P34969 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
HPGD P15428 1/20 0.49
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
USP2 O75604 1/20 0.48
LIG1 P18858 1/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL27188460 0.89 ADRB2 (0.50) ADRB2ADRB1MAPK1TP53RAB9A
SCHEMBL7764770 0.88 HPGD (0.55) ADRB2ADRB1MAPK1HPGDTSHR
SCHEMBL19921086 0.87 ADRB2 (0.48) ADRB2ADRB1MAPK1TP53RAB9A
SCHEMBL6111939 0.86 GAA (0.50) ADRB2ADRB1MAPK1TP53RAB9A
SCHEMBL29107282 0.86 SYK (0.54) ADRB2ADRB1MAPK1TP53RAB9A
SCHEMBL5611931 0.86 ADRB2 (0.47) ADRB2ADRB1MAPK1TP53RAB9A
SCHEMBL11971449 0.85 MAPK1 (0.53) ADRB2ADRB1MAPK1TP53RAB9A
SCHEMBL9431758 0.84 RXRA (0.61) ADRB2ADRB1MAPK1RAB9AHTT
SCHEMBL6665177 0.83 SYK (0.56) ADRB2ADRB1MAPK1TP53HTT
SCHEMBL22085950 0.83 ADRB2 (0.44) ADRB2ADRB1MAPK1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117677671-A Curable resin composition, varnish, prepreg, and cured product 本州化学工业株式会社 2024-03-08 CN claimed
CN-115010613-A Allyl-containing diamine monomer, crosslinkable polyetherimide polymer, crosslinked polyetherimide film and preparation method thereof 大连理工大学盘锦产业技术研究院 2022-09-06 CN claimed
CN-105188852-A Processes for making magnolol derivatives COLGATE PALMOLIVE CO 2015-12-23 CN claimed
EP-3768763-B1 SILICONE POLYMER AND COMPOSITION COMPRISING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2026-04-29 EP disclosed
EP-4719750-A1 EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719753-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4683790-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-01-28 EP disclosed
WO-2025109468-A1 EMBEDDED CONTACT LENS WITH A HIGH REFRACTIVE INDEX INSERT THEREIN ALCON INC. (CH) 2025-05-30 WO disclosed
WO-2024246822-A1 METHOD FOR MAKING EMBEDDED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-12-05 WO disclosed
WO-2024246819-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-12-05 WO disclosed
CN-1829726-A Metathesis catalysts BOEHRINGER INGELHEIM INT (DE) 2006-09-06 CN disclosed
EP-1654266-A1 NOVEL METATHESIS CATALYSTS Boehringer Ingelheim International GmbH (DE) 2006-05-10 EP disclosed
US-20050049417-A1 Metathesis catalysts BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-03-03 US disclosed
WO-2005016944-A1 NOVEL METATHESIS CATALYSTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-02-24 WO disclosed
WO-2004024684-A2 ENANTIOSELECTIVE AMINATION AND ETHERIFICATION YALE UNIVERSITY (US) 2004-03-25 WO disclosed
EP-1248109-A1 Enantiomeric excess determination using a liquid crystal material Rijksuniversiteit te Groningen (NL) 2002-10-09 EP disclosed
EP-0524409-A1 Thermosetting bismaleinimide molding masses BASF Aktiengesellschaft (DE) 1993-01-27 EP disclosed
US-5143969-A Composites with reinforcing fibers BASF AKTIENGESELLSCHAFT (DE) 1992-09-01 US disclosed
EP-0361500-A2 Thermosensitive recording materials MITSUBISHI PAPER MILLS, LTD. (JP) 1990-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049417-A1 Metathesis catalysts CYP1B1, MSMO1, CYP1A1 ADRB2 3774/4885ADRB1 3613/4885MAPK1 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.