SCHEMBL5152336

SCHEMBL5152336

CO[Si](C)(CCCCCCCCC1CO1)OC

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
EPHX1 P07099 1/20 0.35
TDP1 Q9NUW8 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28502412 1.00 ALDH1A1 (0.52) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2
SCHEMBL1096584 0.98 ALDH1A1 (0.48) ALDH1A1EPHX1SMN1; SMN2TSHR
SCHEMBL11004144 0.92 ALDH1A1 (0.45) ALDH1A1TDP1SMN1; SMN2TSHR
SCHEMBL28940059 0.85 ALDH1A1 (0.50) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2
SCHEMBL9615523 0.84 ALDH1A1 (0.52) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2
SCHEMBL662003 0.84 ALDH1A1 (0.52) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2
SCHEMBL661635 0.84 ALDH1A1 (0.52) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2
SCHEMBL22406184 0.84 ALDH1A1 (0.52) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2
SCHEMBL3054646 0.84 ALDH1A1 (0.52) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2
SCHEMBL9417181 0.84 ALDH1A1 (0.52) ALDH1A1EPHX1TDP1SPHK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6433041-B1 None US disclosed
CN-116234847-A Heat-conducting polyurethane composition 陶氏环球技术有限责任公司 2023-06-06 CN disclosed
EP-3504284-B1 PROCESS OF MAKING WATERBORNE LARGE-SIZE AND STABLE SILICONE RUBBER SUSPENSION AND EXCELLENT SENSORY MATTE COATING THEREBY DOW TORAY CO LTD (JP) 2021-01-27 EP disclosed
US-20190194395-A1 PROCESS OF MAKING WATERBORNE LARGE-SIZE AND STABLE SILICONE RUBBER SUSPENSION AND EXCELLENT SENSORY MATTE COATING THEREBY DOW SILICONES CORPORATION 2019-06-27 US disclosed
US-20140273264-A1 EPOXY CHEMISTRY DERIVED MATERIALS AS MIXED MODE CHROMATOGRAPHY MEDIA, METHOD FOR THEIR SYNTHESIS AND USE DIONEX CORPORATION 2014-09-18 US disclosed
WO-2014136806-A1 ORGANOPOLYSILOXANE AND MANUFACTURING METHOD THEREOF DOW CORNING TORAY CO., LTD. (JP) 2014-09-12 WO disclosed
WO-2014136805-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-09-12 WO disclosed
EP-1186641-B1 Water base coating material composition and production process DOW CORNING TORAY CO LTD (JP) 2007-01-17 EP disclosed
EP-1132443-B1 Method for producing water based coating compositions DOW CORNING TORAY SILICONE (JP) 2004-04-21 EP disclosed
US-6710124-B2 SUPERIOR FLAT FINISH PROPERTIES; SILICONE PARTICLES WITH AT LEAST TWO KINDS OF DIFFERENT AVERAGE PARTICLE SIZES. DOW CORNING TORAY SILICONE, CO. LTD. (JP) 2004-03-23 US disclosed
EP-1130046-B1 Method for producing suspension of crosslinked silicone particles DOW CORNING TORAY SILICONE (JP) 2003-07-30 EP disclosed
US-6437042-B2 COMPRISES POLYSILOXANE, CROSSLINKER, AND CONDENSATION CATALYST EMULSIFIED IN WATER USING SURFACTANT; METALLIZATION; PARTICLE DIAMETER; DISPERSION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-08-20 US disclosed
US-6433041-B2 CROSSLINKED SILICONES; WEAR RESISTANT PROTECTIVE COATINGS DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-08-13 US disclosed
US-20020055557-A1 Water base coating material composition and production process DOW TORAY CO., LTD. (JP) 2002-05-09 US disclosed
EP-1186641-A2 Water base coating material composition and production process Dow Corning Toray Silicone Co., Ltd. (JP) 2002-03-13 EP disclosed
EP-1132443-A9 Method for producing water based coating compositions Dow Corning Toray Silicone Company, Ltd. (JP) 2001-10-31 EP disclosed
US-20010027233-A1 Method for producing suspension of crosslinked silicone particles DOW TORAY CO., LTD. (JP) 2001-10-04 US disclosed
US-20010025080-A1 Method for producing water based coating compositions DOW TORAY CO., LTD. (JP) 2001-09-27 US disclosed
EP-1130046-A2 Method for producing suspension of crosslinked silicone particles Dow Corning Toray Silicone Co., Ltd. (JP) 2001-09-05 EP disclosed
EP-1122703-A2 Amusement system having typing practice function, typing practice system, and computer readable storage medium Konami Co., Ltd. (JP) 2001-08-08 EP disclosed