Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155162 | 0.94 | CYSLTR2 (0.54) | CYSLTR2MEN1KMT2AMAPTHRH3 | |
| SCHEMBL5110467 | 0.91 | CYSLTR2 (0.60) | CYSLTR2MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL5125683 | 0.88 | CYSLTR2 (0.61) | CYSLTR2MEN1KMT2AMAPTHRH3 | |
| SCHEMBL14131825 | 0.86 | CYSLTR2 (0.60) | CYSLTR2MEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL5174823 | 0.86 | CYSLTR2 (0.43) | CYSLTR2MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL14145205 | 0.84 | CYSLTR2 (0.61) | CYSLTR2MEN1KMT2AMAPTPLA2G4B | |
| SCHEMBL5155579 | 0.83 | CYSLTR2 (0.44) | CYSLTR2MEN1KMT2AHRH3 | |
| SCHEMBL5113803 | 0.82 | POLB (0.48) | CYSLTR2KMT2AGAAHPGDALDH1A1 | |
| SCHEMBL5155332 | 0.79 | CYSLTR2 (0.45) | CYSLTR2HRH3 | |
| SCHEMBL5118877 | 0.79 | CYSLTR2 (0.58) | CYSLTR2MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740540-A1 | PHENYL ACETAMIDES | Bayer HealthCare AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103001-A1 | PHENYL ACETAMIDES | BAYER HEALTHCARE AG (DE) | 2005-11-03 | — | — | WO | disclosed |