Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152416 | 0.94 | CYSLTR2 (0.52) | CYSLTR2MEN1KMT2AMAPTPDE4B | |
| SCHEMBL5125683 | 0.92 | CYSLTR2 (0.61) | CYSLTR2MEN1KMT2AMAPTPLA2G4B | |
| SCHEMBL5110467 | 0.87 | CYSLTR2 (0.60) | CYSLTR2MEN1KMT2AHRH3 | |
| SCHEMBL14131825 | 0.87 | CYSLTR2 (0.60) | CYSLTR2MEN1KMT2AHRH3 | |
| SCHEMBL14145205 | 0.86 | CYSLTR2 (0.61) | CYSLTR2MEN1KMT2AMAPTPLA2G4B | |
| SCHEMBL5155332 | 0.84 | CYSLTR2 (0.45) | CYSLTR2PPARGPPARAHRH3 | |
| SCHEMBL5155579 | 0.84 | CYSLTR2 (0.44) | CYSLTR2MEN1KMT2APLA2G2DHRH3 | |
| SCHEMBL5118730 | 0.81 | CYSLTR2 (0.48) | CYSLTR2MEN1KMT2AHRH3 | |
| SCHEMBL5118877 | 0.81 | CYSLTR2 (0.58) | CYSLTR2MEN1KMT2AMAPTPDE4B | |
| SCHEMBL5174823 | 0.81 | CYSLTR2 (0.43) | CYSLTR2MEN1KMT2AMAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740540-A1 | PHENYL ACETAMIDES | Bayer HealthCare AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103001-A1 | PHENYL ACETAMIDES | BAYER HEALTHCARE AG (DE) | 2005-11-03 | — | — | WO | disclosed |