Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 3/20 | 0.36 |
| ▸ | NMT1 | P30419 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5124864 | 0.90 | CYSLTR2 (0.48) | CYSLTR2HRH3KMT2AITGB3ITGA2B | |
| SCHEMBL5211440 | 0.87 | CYSLTR2 (0.50) | CYSLTR2HRH3KMT2AITGB3ITGA2B | |
| SCHEMBL5155162 | 0.84 | CYSLTR2 (0.54) | CYSLTR2HRH3KMT2AMEN1PLA2G2D | |
| SCHEMBL5173022 | 0.84 | NMT2 (0.39) | CYSLTR2HRH3KMT2ANMT2NMT1 | |
| SCHEMBL5152416 | 0.83 | CYSLTR2 (0.52) | CYSLTR2HRH3KMT2AMEN1 | |
| SCHEMBL5151988 | 0.83 | YAP1 (0.38) | CYSLTR2KMT2AMEN1PLA2G2D | |
| SCHEMBL14131825 | 0.82 | CYSLTR2 (0.60) | CYSLTR2HRH3KMT2AMEN1 | |
| SCHEMBL5117054 | 0.79 | CYSLTR2 (0.46) | CYSLTR2HRH3KMT2AITGB3ITGA2B | |
| SCHEMBL5115310 | 0.79 | ALDH1A1 (0.44) | HRH3KMT2ANMT2NMT1MEN1 | |
| SCHEMBL5114501 | 0.79 | CYSLTR2 (0.48) | CYSLTR2ITGB3ITGA2BPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740540-A1 | PHENYL ACETAMIDES | Bayer HealthCare AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103001-A1 | PHENYL ACETAMIDES | BAYER HEALTHCARE AG (DE) | 2005-11-03 | — | — | WO | disclosed |