SCHEMBL5152941

SCHEMBL5152941

O=C(O)CCc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.44
FFAR1 O14842 5/20 0.42
FFAR4 Q5NUL3 2/20 0.42
KEAP1 Q14145 1/20 0.42
GPR17 Q13304 1/20 0.41
PTGER1 P34995 2/20 0.41
PTGER4 P35408 2/20 0.41
PTGER3 P43115 2/20 0.41
PTGER2 P43116 2/20 0.41
POLB P06746 1/20 0.41
HDAC3 O15379 1/20 0.39
MAPK1 P28482 1/20 0.39
ADRA1A P35348 1/20 0.39
HDAC4 P56524 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4699564 0.82 TAAR1 (0.55) NPSR1FFAR1KEAP1GPR17PTGER1
SCHEMBL4900831 0.81 CXCL8 (0.50) ADRA1A
Hydrochloric Acid SCHEMBL11408340 0.79 CXCL8 (0.49) ADRA1A
SCHEMBL25224754 0.77 GPR17 (0.49) NPSR1FFAR1FFAR4KEAP1GPR17
SCHEMBL6609425 0.77 POLB (0.46) NPSR1FFAR1FFAR4KEAP1PTGER1
SCHEMBL1768167 0.77 PTGER1 (0.54) FFAR1FFAR4KEAP1PTGER1PTGER4
SCHEMBL11111891 0.77 POLB (0.50) NPSR1FFAR1FFAR4KEAP1POLB
SCHEMBL1694578 0.76 TAAR1 (0.52) NPSR1FFAR1PTGER1PTGER4PTGER3
SCHEMBL30278649 0.76 PARP1 (0.50) FFAR1FFAR4KEAP1GPR17HDAC3
SCHEMBL586345 0.74 PDPK1 (0.59) FFAR1GPR17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281080-A4 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LAB INC (US) 2006-03-22 EP claimed
US-20030211618-A1 Color changing steam sterilization indicator JP LABORATORIES, INC. 2003-11-13 US claimed
EP-1281080-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2003-02-05 EP claimed
WO-2001086289-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2001-11-15 WO claimed
EP-1165151-B1 INDICATORS FOR MONITORING STERILIZATION WITH PLASMA PATEL GORDHANBHAI N (US) 2007-01-03 EP disclosed
EP-1281080-A4 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LAB INC (US) 2006-03-22 EP disclosed
US-20030211618-A1 Color changing steam sterilization indicator JP LABORATORIES, INC. 2003-11-13 US disclosed
EP-1281080-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2003-02-05 EP disclosed
EP-1165151-A1 INDICATORS FOR MONITORING STERILIZATION WITH PLASMA Patel, Gordhanbhai N. (US) 2002-01-02 EP disclosed
WO-2001086289-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2001-11-15 WO disclosed
WO-2000061200-A1 INDICATORS FOR MONITORING STERILIZATION WITH PLASMA PATEL GORDHANBHAI N (US) 2000-10-19 WO disclosed