Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486019 | 0.83 | PTGS1 (0.49) | ADRA1ACYP2C9HTTTDP1CLCN2 | |
| SCHEMBL1768328 | 0.80 | MEN1 (0.46) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL8479912 | 0.79 | PTGER4 (0.70) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL5440013 | 0.79 | FFAR4 (0.66) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL3746360 | 0.79 | FFAR4 (0.66) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL5152941 | 0.77 | NPSR1 (0.44) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL31212507 | 0.77 | PTGER4 (0.77) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL1261128 | 0.77 | PTGER4 (0.77) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL5153010 | 0.77 | FFAR4 (0.53) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL6053663 | 0.75 | PTGER4 (0.81) | PTGER1PTGER4PTGER3PTGER2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061271-A1 | SUBSTITUTED CARBAMOYLMETHYLAMINO ACETIC ACID DERIVATIVES AS NOVEL NEP INHIBITORS | NOVARTIS AG (CH) | 2011-05-26 | — | — | WO | disclosed |