Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338579 | 0.73 | KDM1A (0.33) | KDM1AMAOAMAOB | |
| SCHEMBL7511837 | 0.70 | KDM1A (0.40) | CHRNA7KDM1AMAOAMAOB | |
| SCHEMBL9466795 | 0.70 | CHRNA7 (0.34) | CHRNA7KDM1AMAOAMAOBATM | |
| SCHEMBL5843679 | 0.70 | HTR2A (0.36) | KDM1AMAOAMAOB | |
| SCHEMBL5185255 | 0.70 | POLB (0.34) | KDM1AMAOAMAOB | |
| SCHEMBL7199456 | 0.67 | CHRNA7 (0.41) | CHRNA7KDM1AMAOAMAOB | |
| SCHEMBL7430840 | 0.67 | KDM1A (0.31) | KDM1AMAOAMAOB | |
| SCHEMBL5576897 | 0.67 | KDM1A (0.31) | KDM1AMAOAMAOB | |
| SCHEMBL8077336 | 0.67 | KDM1A (0.38) | KDM1AMAOAMAOB | |
| SCHEMBL4234394 | 0.67 | POLB (0.37) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633699-B1 | ARYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS | WYETH CORP (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1633699-A2 | ARYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS | Wyeth (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004103941-A2 | ARYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS | WYETH (US) | 2004-12-02 | — | — | WO | disclosed |