⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787125 | 0.98 | CASP2 (0.62) | — | |
| SCHEMBL2860384 | 0.93 | CA12 (0.59) | — | |
| SCHEMBL27669913 | 0.91 | CA12 (0.56) | — | |
| SCHEMBL7526271 | 0.91 | CA12 (0.56) | — | |
| Hydrochloric Acid SCHEMBL9347137 | 0.91 | LMNA (0.61) | — | |
| SCHEMBL6326924 | 0.91 | CA12 (0.56) | — | |
| SCHEMBL8007181 | 0.90 | CA12 (0.57) | — | |
| SCHEMBL1260151 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL9342148 | 0.88 | UBE2N (0.59) | — | |
| SCHEMBL11875682 | 0.87 | CA12 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803485-B | Preparation method and preparation system of continuous aminopropionitrile mixture | 安徽恒光聚氨酯材料有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-116803485-A | Preparation method and preparation system of continuous aminopropionitrile mixture | 安徽恒光聚氨酯材料有限公司 | 2023-09-26 | — | — | CN | disclosed |
| US-9944836-B2 | Amine composition | EVONIK DEGUSSA GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| CN-105936824-A | Soil heavy metal activator and preparation method and application thereof | 深圳多元拓展环保科技有限公司 | 2016-09-14 | — | — | CN | disclosed |
| EP-1749522-A2 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases | NPS PHARMACEUTICALS, INC. (US) | 2007-02-07 | — | — | EP | disclosed |
| EP-1123922-B1 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases | NPS PHARMA INC (US) | 2006-11-29 | — | — | EP | disclosed |
| JP-2004155822-A | CLEANING AGENT | TOSOH CORP | 2004-06-03 | — | — | JP | disclosed |
| CN-1088585-C | Compound active at a novel site on receptor-operated calcium channels usefull for treatment of neurological disorders and diseases | NPS PHARMACEUTICAL CO LTD (US) | 2002-08-07 | — | — | CN | disclosed |
| US-6306912-B1 | POLYAMINO CARBONYLAMINO ALKYL FLUORO SUBSTITUTES INDOLE COMPOUNDS | NPS PHARMACEUTICALS, INC. | 2001-10-23 | — | — | US | disclosed |
| EP-1123922-A2 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases | NPS PHARMACEUTICALS, INC. (US) | 2001-08-16 | — | — | EP | disclosed |
| US-6071970-A | FOR TREATING PATIENTS HAVING NEUROLOGICAL DISEASE OR DISORDER, SUCH AS STROKE, HEAD TRAUMA, SPINAL CORD INJURY, EPILEPSY, ANXIETY, OR NEURODEGENERATIVE DISEASES SUCH AS ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, PARKINSON'S DISEASE | NPS PHARMACEUTICALS, INC. (US) | 2000-06-06 | — | — | US | disclosed |
| US-6051610-A | COMPOUNDS USEFUL AS NEUROPROTECTANTS, ANTICONVULSANTS, ANXIOLYTICS, ANALGESICS, MUSCLE RELAXANTS OR ADJUVANTS TO GENERAL ANESTHETICS | NPS PHARMACEUTICALS, INC. (US) | 2000-04-18 | — | — | US | disclosed |
| CN-1148337-A | Compound active at a novel site on receptor-operated calcium channels usefull for treatment of neurological disorders and diseases | NPS PHARMACEUTICAL CO LTD (US) | 1997-04-23 | — | — | CN | disclosed |
| EP-0743853-A1 | COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES | NPS PHARMACEUTICALS, INC. (US) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021612-A2 | COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES | NPS PHARMACEUTICALS, INC. (US) | 1995-08-17 | — | — | WO | disclosed |
| US-5426192-A | Heat or pressure sensitive recording materials | CIBA-GEIGY CORPORATION (US) | 1995-06-20 | — | — | US | disclosed |
| US-5329006-A | Heat and pressure sensitive elements for copies | CIBA-GEIGY CORPORATION (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0475908-A1 | Chromogenic lactam compounds, their production and use | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| EP-0037861-A1 | Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-21 | — | — | EP | disclosed |