Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586902 | 0.83 | HTR2A (0.52) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL6580105 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL6580098 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL6580101 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL11353001 | 0.82 | AOC3 (0.70) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL6577083 | 0.82 | AOC3 (0.70) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL21340477 | 0.82 | AOC3 (0.70) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL19658276 | 0.82 | AOC3 (0.70) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL6580072 | 0.82 | AOC3 (0.70) | KDM4EALDH1A1AOC3CYP2C9MEN1 | |
| SCHEMBL19658275 | 0.82 | AOC3 (0.70) | KDM4EALDH1A1AOC3CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497272-A4 | METHOD OF PREPARING AMINE STEREOISOMERS | APSINTERM LLC (US) | 2007-02-07 | — | — | EP | claimed |
| EP-1497272-A2 | METHOD OF PREPARING AMINE STEREOISOMERS | Apsinterm, LLC. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003091207-A2 | METHOD OF PREPARING AMINE STEREOISOMERS | APSINTERM, LLC. (US) | 2003-11-06 | — | — | WO | claimed |