SCHEMBL7586902

SCHEMBL7586902

CN(C)C(c1ccccc1)C(c1ccccc1)N(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.52
HRH1 P35367 4/20 0.52
AOC3 Q16853 7/20 0.52
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
SLC6A2 P23975 3/20 0.45
SLC6A4 P31645 3/20 0.45
LMNA P02545 2/20 0.45
CYP1A2 P05177 1/20 0.45
CHRM2 P08172 1/20 0.45
CHRM4 P08173 1/20 0.45
CHRM5 P08912 1/20 0.45
ADRA2A P08913 1/20 0.45
CYP2D6 P10635 1/20 0.45
CHRM1 P11229 1/20 0.45
TSHR P16473 1/20 0.45
ADRA2B P18089 1/20 0.45
CHRM3 P20309 1/20 0.45
HRH2 P25021 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2453015 0.92 AOC3 (0.47) HTR2AHRH1AOC3KDM4EALDH1A1
SCHEMBL10125298 0.87 KDM4E (0.50) HTR2AHRH1AOC3KDM4EALDH1A1
SCHEMBL22725637 0.87 KDM4E (0.50) HTR2AHRH1AOC3KDM4EALDH1A1
Hydrochloric Acid SCHEMBL14764229 0.85 ALDH1A1 (0.48) HTR2AHRH1AOC3KDM4EALDH1A1
SCHEMBL19658275 0.83 AOC3 (0.70) HTR2AAOC3KDM4EALDH1A1SLC6A2
SCHEMBL21340477 0.83 AOC3 (0.70) HTR2AAOC3KDM4EALDH1A1SLC6A2
SCHEMBL6920099 0.83 DPP4 (0.56) HTR2AHRH1AOC3KDM4EALDH1A1
SCHEMBL6580072 0.83 AOC3 (0.70) HTR2AAOC3KDM4EALDH1A1SLC6A2
SCHEMBL11353001 0.83 AOC3 (0.70) HTR2AAOC3KDM4EALDH1A1SLC6A2
SCHEMBL17571131 0.83 AOC3 (0.53) HTR2AHRH1AOC3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst MITSUI CHEMICALS, INC. (JP) 2023-07-04 US disclosed
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst MITSUI CHEMICALS, INC. (JP) 2023-07-04 US disclosed
US-20200222886-A1 OLEFIN OLIGOMERIZATION CATALYST AND METHOD FOR PRODUCING OLEFIN OLIGOMER IN THE PRESENCE OF THE SAME CATALYST MITSUI CHEMICALS, INC. (JP) 2020-07-16 US disclosed
EP-0803510-B1 2,2'-Disubstituted 1,1'-diphosphino ferrocenes and 1',2-disubstituted 1-phosphino ferrocenes, their preparation and use and transition metal complexes containing them HOECHST AG (DE) 2002-09-11 EP disclosed
US-5856540-A 2,2'-disubtituted 1,1'-diphosphino-ferrocenes and 1',2-disubstituted 1-phosphino-ferrocenes, processes for preparing them, their use, and transition metal complexes comprising them HOECHST AKTIENGESELLSCHAFT (DE) 1999-01-05 US disclosed
EP-0803510-A1 2,2'-Disubstituted 1,1'-diphosphino ferrocenes and 1',2'-disubstituted 1-phosphino ferrocenes, their preparation and use and transition metal complexes containing them HOECHST AKTIENGESELLSCHAFT (DE) 1997-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200222886-A1 OLEFIN OLIGOMERIZATION CATALYST AND METHOD FOR PRODUCING OLEFIN OLIGOMER IN THE PRESENCE OF THE SAME CATALYST OXER1, COG6, CBR1 HTR2A 1012/4885HRH1 148/4885AOC3 19/4885
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst OXER1, COG6, CBR1 HTR2A 1012/4885HRH1 148/4885AOC3 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.