Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658277 | 1.00 | AOC3 (0.70) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL19658276 | 1.00 | AOC3 (0.70) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL11353001 | 1.00 | AOC3 (0.70) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL21340477 | 1.00 | AOC3 (0.70) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL19658275 | 1.00 | AOC3 (0.70) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL6580072 | 1.00 | AOC3 (0.70) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL7586902 | 0.83 | HTR2A (0.52) | AOC3KDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL6742085 | 0.83 | AOC3 (1.00) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL15139983 | 0.83 | AOC3 (1.00) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 | |
| SCHEMBL6742087 | 0.83 | AOC3 (1.00) | AOC3KDM4EALDH1A1ADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179536-A1 | METHOD OF SYNTHESIZING (1R,2R)-NITROALCOHOL COMPOUND | SICHUAN UNIVERSITY (CN) | 2021-06-17 | — | — | US | claimed |
| CN-110878024-A | Synthesis method of (1R,2R) -nitroalcohol compound | 四川大学 | 2020-03-13 | — | — | CN | claimed |
| US-11623913-B2 | Method of synthesizing (1R,2R)-nitroalcohol compound | SICHUAN UNIVERSITY (CN) | 2023-04-11 | — | — | US | disclosed |
| US-20210179536-A1 | METHOD OF SYNTHESIZING (1R,2R)-NITROALCOHOL COMPOUND | SICHUAN UNIVERSITY (CN) | 2021-06-17 | — | — | US | disclosed |
| CN-110878024-B | Synthesis method of (1R,2R) -nitroalcohol compound | 四川大学 | 2021-02-26 | — | — | CN | disclosed |
| CN-110878024-A | Synthesis method of (1R,2R) -nitroalcohol compound | 四川大学 | 2020-03-13 | — | — | CN | disclosed |
| US-7692019-B2 | Methods for the stereoselective synthesis of substituted piperidines | SEPRACOR INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20040236118-A1 | Pyrrolidine derivatives and method of synthesizing these | EIZAI CO., LTD (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1413574-A1 | PYRROLIDINE DERIVATIVES AND METHOD OF SYNTHESIZING THESE | Eizai Co., Ltd. (JP) | 2004-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236118-A1 | Pyrrolidine derivatives and method of synthesizing these | ADH1C, ADH5, ADH1A | AOC3 1294/4885KDM4E 1456/4885ALDH1A1 145/4885 |
| US-20210179536-A1 | METHOD OF SYNTHESIZING (1R,2R)-NITROALCOHOL COMPOUND | ADH1C, ADH1A, CBR1 | AOC3 23/4885KDM4E 4110/4885ALDH1A1 18/4885 |
| US-11623913-B2 | Method of synthesizing (1R,2R)-nitroalcohol compound | ADH1C, ADH1A, CBR1 | AOC3 23/4885KDM4E 4110/4885ALDH1A1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.