Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154050 | 1.00 | LMNA (0.57) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL2878053 | 0.92 | LMNA (0.61) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL128637 | 0.92 | ALDH1A1 (0.61) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL28338856 | 0.92 | LMNA (0.61) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL314047 | 0.86 | LMNA (0.54) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL30899588 | 0.83 | ALDH1A1 (0.58) | LMNAALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL28112894 | 0.82 | LMNA (0.59) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL28319044 | 0.82 | LMNA (0.59) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL4630852 | 0.82 | ALDH1A1 (0.50) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 | |
| SCHEMBL30525900 | 0.80 | ALDH1A1 (0.56) | LMNAALDH1A1CYP2D6SPHK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1738803-A1 | Inhibitors of staphylococcus hominis in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-01-03 | — | — | EP | claimed |
| EP-1576946-A1 | Use of inhibitors of gram-positive cocci in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| EP-1738803-A1 | Inhibitors of staphylococcus hominis in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1576946-A1 | Use of inhibitors of gram-positive cocci in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | disclosed |