Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541594 | 1.00 | NAAA (0.67) | NAAAFAAH | |
| SCHEMBL10045399 | 0.84 | NAAA (0.57) | NAAAFAAH | |
| SCHEMBL524458 | 0.80 | KDM4E (0.56) | — | |
| SCHEMBL523656 | 0.80 | KDM4E (0.56) | — | |
| SCHEMBL524333 | 0.80 | KDM4E (0.56) | — | |
| SCHEMBL13345791 | 0.80 | NAAA (0.68) | NAAAFAAH | |
| SCHEMBL14206854 | 0.80 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19490715 | 0.77 | NAAA (0.54) | NAAA | |
| SCHEMBL14642159 | 0.77 | NAAA (0.40) | NAAA | |
| SCHEMBL19825342 | 0.76 | NAAA (0.80) | NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414339-B1 | KINETIC RESOLUTION OF (4S)-4-PHENYL-3-[5(RS)-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-1,3 OXAZOLIDIN 2-ONE TO (5S) ISOMER VIA LIPASE CATALYZED ENANTIOSELECTIVE ESTERIFICATION OF THE (5R) ISOMER | LUPIN LTD (IN) | 2013-01-16 | — | — | EP | claimed |
| US-8178665-B2 | Process for the production of ezetimibe and intermediates used in this process | RICHTER GEDEON NYRT. (HU) | 2012-05-15 | — | — | US | disclosed |
| EP-2414339-A1 | KINETIC RESOLUTION OF (4S)-4-PHENYL-3-Ý5(RS)-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL¨-1,3 OXAZOLIDIN 2-ONE TO (5S) ISOMER VIA LIPASE CATALYZED ENANTIOSELECTIVE ESTERIFICATION OF THE (5R) ISOMER | Lupin Ltd. (IN) | 2012-02-08 | — | — | EP | disclosed |
| US-20120028340-A1 | KINETIC RESOLUTION OF (4S) -- 4- PHENYL -- 3- [(5RS)-5-(4-FLUROPHENYL)-5- HYDROXYPENTANOYL] --1,3-OXAZOLIDIN-2-ONE TO THE (5S) ISOMER VIA LIPASE CATALYZED ENANTIOSELECTIVE ESTERIFICATION OF THE (5R) ISOMER | LUPIN LIMITED (IN) | 2012-02-02 | — | — | US | disclosed |
| EP-1963260-B1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCESS | RICHTER GEDEON NYRT (HU) | 2010-11-03 | — | — | EP | disclosed |
| US-20090216009-A1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCESS | RICHTER GEDEON NYRT. (HU) | 2009-08-27 | — | — | US | disclosed |
| EP-1963260-A1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCES | Richter Gedeon NYRT (HU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072088-A1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCES | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216009-A1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCESS | APOB, HMGCR, PCSK9 | NAAA 1839/4885FAAH 1302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.