Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MYOC | Q99972 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149500 | 0.89 | MEN1 (0.53) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL5149577 | 0.87 | MEN1 (0.50) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL5149668 | 0.85 | BRAF (0.49) | MAPTMAPK1NPSR1RAF1CA12 | |
| SCHEMBL11833078 | 0.82 | MEN1 (0.76) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL5184379 | 0.77 | TBXA2R (0.52) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL4786545 | 0.74 | MEN1 (0.50) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL5184278 | 0.74 | TBXA2R (0.53) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL620645 | 0.74 | KMT2A (0.51) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL4686268 | 0.74 | PKM (0.53) | MEN1KMT2AMAPK1PKMPPARG | |
| SCHEMBL4237333 | 0.74 | PKM (0.50) | RAB9ANPC1PKMSMN1; SMN2RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |