Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 8/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.49 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | ARAF | P10398 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684325 | 0.88 | MAPK1 (0.43) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL4237333 | 0.88 | PKM (0.50) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL13699200 | 0.87 | MAPK1 (0.42) | PNLIPALOX5CA12CA1CA2 | |
| SCHEMBL5149550 | 0.85 | PNLIP (0.39) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5153593 | 0.85 | MEN1 (0.51) | RAF1CA12CA1CA2CA9 | |
| SCHEMBL4232176 | 0.82 | FPR2 (0.46) | MAPTMAPK1 | |
| SCHEMBL5181890 | 0.82 | PNLIP (0.55) | PNLIPMAPTNPSR1GCGR | |
| SCHEMBL4685589 | 0.81 | EPHX1 (0.50) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5180344 | 0.81 | MMP2 (0.42) | PNLIPCA12CA1CA2CA9 | |
| SCHEMBL5151701 | 0.80 | TBXA2R (0.48) | CA12CA1CA2CA9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |