Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732335 | 0.98 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3936649 | 0.84 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9492107 | 0.82 | CA1 (0.64) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3936655 | 0.81 | CA1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27074522 | 0.81 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL187271 | 0.80 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL22193556 | 0.80 | MMP13 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28494294 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5931096 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28499035 | 0.79 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572104-A4 | INDUCTION OF APOPTOSIS BY HIV-1 INFECTED MONOCYTIC CELLS | SPERBER KIRK (US) | 2007-01-17 | — | — | EP | disclosed |
| EP-1572104-A2 | INDUCTION OF APOPTOSIS BY HIV-1 INFECTED MONOCYTIC CELLS | Sperber, Kirk (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1572104-A3 | INDUCTION OF APOPTOSIS BY HIV-1 INFECTED MONOCYTIC CELLS | Sperber, Kirk (US) | 2005-08-18 | — | — | EP | disclosed |
| US-20040197770-A1 | Induction of apoptosis by HIV-1 infected monocytic cells | MOUNT SINAI SCHOOL OF MEDICINE | 2004-10-07 | — | — | US | disclosed |
| WO-2004045519-A2 | INDUCTION OF APOPTOSIS BY HIV-1 INFECTED MONOCYTIC CELLS | SPERBER KIRK (US) | 2004-06-03 | — | — | WO | disclosed |