Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL5153720 | 0.98 | CA1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3936649 | 0.85 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9492107 | 0.84 | CA1 (0.64) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3936655 | 0.83 | CA1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27074522 | 0.82 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL187271 | 0.81 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL22193556 | 0.81 | MMP13 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28494294 | 0.81 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5931096 | 0.81 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28499035 | 0.80 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479432-B1 | STORAGE-STABLE NON-AQUEOUS OR LOW-WATER SUSPENSION CONCENTRATES IN THE FORM OF SUSPENSIONS WHICH COMPRISE AT LEAST ONE SOLID, SPECIFICALLY FROM THE GROUP OF THE HERBICIDAL SULFONYLUREAS | AVENTIS CROPSCIENCE GMBH (DE) | 2002-11-12 | — | — | US | claimed |
| US-5698539-A | PLANT SAFENING AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | claimed |
| CN-1049656-A | Replace N-(quinoline-2-base-methoxyl group) benzyl sulfonylurea | BAYER AG (DE) | 1991-03-06 | — | — | CN | claimed |
| US-11628161-B2 | Isoindoline derivative, pharmaceutical composition and use thereof | KANGPU BIOPHARMACEUTICALS, LTD. (CN) | 2023-04-18 | — | — | US | disclosed |
| US-11337964-B2 | Isoindoline derivative, pharmaceutical composition and use thereof | KANGPU BIOPHARMACEUTICALS, LTD. (CN) | 2022-05-24 | — | — | US | disclosed |
| US-20220152002-A1 | ISOINDOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | KANGPU BIOPHARMACEUTICALS, LTD. (CN) | 2022-05-19 | — | — | US | disclosed |
| EP-3921349-A1 | PHENYL ISOCYANATE CONVERSION PROCESS | Dow Global Technologies LLC (US) | 2021-12-15 | — | — | EP | disclosed |
| CN-214075426-U | Filtration extraction element of p-toluenesulfonylurea | 吉安市海洲医药化工有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-111818919-A | Imipritone for glioma | 昂克希尔迪克斯有限公司 | 2020-10-23 | — | — | CN | disclosed |
| WO-2020163092-A1 | PHENYL ISOCYANATE CONVERSION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-08-13 | — | — | WO | disclosed |
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-4609395-A | Novel benzylsulfonylureas and arylsulfamoylureas N-[(substituted pyrimidin-2-yl)aminocarbonyl]-1-oxo-fused benzyl-7-methanesulfonamides useful as herbicides and plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4609395-A | Novel benzylsulfonylureas and arylsulfamoylureas N-[(substituted pyrimidin-2-yl)aminocarbonyl]-1-oxo-fused benzyl-7-methanesulfonamides useful as herbicides and plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4565567-A | Herbicidal heterocyclic alkylaminocarbonylsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-21 | — | — | US | disclosed |
| US-4496392-A | Herbicidal heterocyclic alkylaminocarbonylsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0051466-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-09 | — | — | EP | disclosed |
| US-4454334-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4454334-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4420325-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
| US-4420325-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11337964-B2 | Isoindoline derivative, pharmaceutical composition and use thereof | PDE4A, PDE4B, PDE4C | CA1 1884/4885CA2 1288/4885MMP1 173/4885 |
| US-11628161-B2 | Isoindoline derivative, pharmaceutical composition and use thereof | PDE4A, PDE4B, PDE4C | CA1 1884/4885CA2 1288/4885MMP1 173/4885 |
| US-20220152002-A1 | ISOINDOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PDE4A, PDE4B, PDE4C | CA1 1832/4885CA2 1253/4885MMP1 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.