Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | VDR | P11473 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158570 | 0.92 | HDAC6 (0.47) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL5156974 | 0.91 | VDR (0.48) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL5158573 | 0.88 | HDAC6 (0.54) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL5158564 | 0.88 | HDAC6 (0.54) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL5159870 | 0.85 | HDAC6 (0.45) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL5159864 | 0.85 | HDAC6 (0.45) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL2963670 | 0.85 | HDAC6 (0.48) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL12764247 | 0.81 | HDAC6 (0.38) | HDAC6HDAC3VDRAR | |
| SCHEMBL1524963 | 0.81 | HDAC3 (0.37) | HDAC6HDAC3VDR | |
| SCHEMBL1524886 | 0.80 | ESR1 (0.49) | HDAC6HDAC3VDRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740522-A2 | BISPHENYL COMPOUNDS USEFUL AS VITAMIN D SB 3 /SB RECEPTOR AGONISTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20060025474-A1 | Bisphenyl compounds useful as vitamin D3 receptor agonists | CHUGAI SEIYAKU KABUSHIKA KAISHA (JP) | 2006-02-02 | — | — | US | disclosed |
| WO-2005087700-A2 | BISPHENYL COMPOUNDS USEFUL AS VITAMIN D3 RECEPTOR AGONISTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025474-A1 | Bisphenyl compounds useful as vitamin D3 receptor agonists | VDR, CYP2R1, CYP24A1 | HDAC6 4385/4885HDAC3 1080/4885VDR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.