Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.56 |
| ▸ | CTSB | P07858 | 18/20 | 0.56 |
| ▸ | CTSL | P07711 | 17/20 | 0.56 |
| ▸ | CTSK | P43235 | 14/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272850 | 0.85 | CTSS (0.63) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1273524 | 0.85 | CTSS (0.63) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1272502 | 0.82 | CTSS (0.65) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1272837 | 0.80 | CTSS (0.80) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1272917 | 0.80 | CTSS (0.80) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1272506 | 0.77 | CTSS (0.59) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1271794 | 0.77 | CTSL (0.57) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1273437 | 0.76 | CTSL (0.48) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1272793 | 0.76 | CTSS (0.61) | CTSSCTSBCTSLCTSK | |
| SCHEMBL1271799 | 0.76 | CTSS (0.61) | CTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866277-A2 | SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | CELERA GENOMICS (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006102535-A2 | SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | CELERA GENOMICS (US) | 2006-09-28 | — | — | WO | claimed |