Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 16/20 | 0.61 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780392 | 0.87 | ALDH1A1 (0.74) | GRIK1KDM4EALDH1A1GLAGAA | |
| SCHEMBL16907485 | 0.84 | NPSR1 (0.61) | GRIK1KDM4EALDH1A1GLAGAA | |
| SCHEMBL29739599 | 0.84 | NPSR1 (0.61) | GRIK1KDM4EALDH1A1GLAGAA | |
| SCHEMBL3779399 | 0.83 | ALDH1A1 (0.57) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL3782993 | 0.82 | ALDH1A1 (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL11184124 | 0.82 | NPC1 (0.63) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL5169945 | 0.81 | ALDH1A1 (0.57) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL29659875 | 0.81 | ALDH1A1 (0.57) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL29739697 | 0.80 | KMT2A (0.70) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL21319206 | 0.79 | RAB9A (0.60) | GRIK1KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174151-B1 | THERAPEUTIC TREATMENT OF EOSINOPHILIA USING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT | DAIICHI ASUBIO PHARMA CO LTD (JP) | 2007-01-24 | — | — | EP | disclosed |
| EP-1192950-B1 | THERAPEUTIC DRUGS FOR DERMATITIS EXHIBITING A BIPHASIC SKIN REACTION CONTAINING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT | DAIICHI ASUBIO PHARMA CO LTD (JP) | 2006-07-26 | — | — | EP | disclosed |
| EP-1114035-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNTORY LIMITED (JP) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000010982-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEROF | SUNTORY LIMITED (JP) | 2000-03-02 | — | — | WO | disclosed |