Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375758 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28117527 | 0.76 | CES1 (0.47) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL297104 | 0.74 | ALDH1A1 (0.56) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28949242 | 0.74 | ALDH1A1 (0.56) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9422343 | 0.74 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10917315 | 0.72 | CYP2C19 (0.41) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9806676 | 0.72 | CYP2C19 (0.43) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2138575 | 0.72 | CYP2C19 (0.43) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2130744 | 0.70 | CYP1A2 (0.46) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11850439 | 0.70 | KCNN4 (0.38) | ALDH1A1ALOX15CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740947-A2 | FLUORESCENT DYES AND COMPLEXES | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005098437-A2 | FLUORESCENT DYES AND COMPLEXES | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD (GB) | 2005-10-20 | — | — | WO | disclosed |