Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6012029 | 0.82 | LMNA (0.75) | MAPTLMNAALDH1A1CYP3A4NR1I2 | |
| SCHEMBL5189196 | 0.82 | LMNA (0.75) | MAPTLMNAALDH1A1CYP3A4NR1I2 | |
| SCHEMBL5155074 | 0.82 | LMNA (0.55) | MAPTLMNAHIF1AALDH1A1MCL1 | |
| Nandrolone Phenpropionate SCHEMBL8443 | 0.77 | MAPT (1.00) | MAPTLMNAHIF1AALDH1A1MCL1 | |
| Nandrolone Phenpropionate SCHEMBL15285479 | 0.77 | MAPT (1.00) | MAPTLMNAHIF1AALDH1A1MCL1 | |
| Nandrolone Phenpropionate SCHEMBL29396630 | 0.77 | MAPT (1.00) | MAPTLMNAHIF1AALDH1A1MCL1 | |
| Testosterone Phenylacetate SCHEMBL547375 | 0.76 | CYP3A4 (0.76) | MAPTLMNAHIF1AALDH1A1HSD17B10 | |
| SCHEMBL5153517 | 0.76 | MAPT (0.52) | MAPTLMNAHIF1AALDH1A1MCL1 | |
| SCHEMBL31304050 | 0.75 | SERPINA6 (0.67) | MAPTLMNAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL6024545 | 0.75 | SERPINA6 (0.67) | MAPTLMNAALDH1A1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262023-B2 | Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-Halogen steroids and uses thereof | BAYER SCHERING PHARMA AG (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20050090477-A1 | Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-halogen steroids that can be produced therefrom, their process for production and use as well as pharmaceutical prepartions that contain these compounds, as well as 7-substituted estra-1,3,5(10)-trienses that can be produced therefrom | SCHERING AG (DE) | 2005-04-28 | — | — | US | disclosed |
| EP-1353938-A1 | ANDROGENIC 7-SUBSTITUTED 11-HALOGENATED STEROIDS | Schering Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002059139-A1 | ANDROGENIC 7-SUBSTITUTED 11-HALOGEN STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | WO | disclosed |