Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PGR | P06401 | 3/20 | 0.54 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189196 | 0.86 | LMNA (0.75) | LMNAMAPTCYP3A4KMT2APGR | |
| SCHEMBL6012029 | 0.86 | LMNA (0.75) | LMNAMAPTCYP3A4KMT2APGR | |
| SCHEMBL17419486 | 0.85 | LMNA (0.74) | LMNAMAPTCYP3A4KMT2APGR | |
| SCHEMBL604525 | 0.85 | LMNA (0.73) | LMNAMAPTCYP3A4KMT2APGR | |
| SCHEMBL5155136 | 0.82 | MAPT (0.62) | LMNAMAPTCYP3A4KMT2APGR | |
| SCHEMBL5153517 | 0.81 | MAPT (0.52) | LMNAMAPTCYP3A4KMT2APGR | |
| Testosterone Cypionate SCHEMBL6151889 | 0.76 | CYP3A4 (0.76) | LMNAMAPTCYP3A4KMT2APGR | |
| Testosterone Cypionate SCHEMBL40862 | 0.76 | CYP3A4 (0.76) | LMNAMAPTCYP3A4KMT2APGR | |
| Testosterone Cypionate SCHEMBL12754434 | 0.76 | CYP3A4 (0.76) | LMNAMAPTCYP3A4KMT2APGR | |
| Testosterone Cypionate SCHEMBL16210495 | 0.76 | CYP3A4 (0.76) | LMNAMAPTCYP3A4KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262023-B2 | Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-Halogen steroids and uses thereof | BAYER SCHERING PHARMA AG (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20050090477-A1 | Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-halogen steroids that can be produced therefrom, their process for production and use as well as pharmaceutical prepartions that contain these compounds, as well as 7-substituted estra-1,3,5(10)-trienses that can be produced therefrom | SCHERING AG (DE) | 2005-04-28 | — | — | US | disclosed |