Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841553 | 0.84 | NPC1 (0.59) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL6960400 | 0.83 | NPC1 (0.53) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL7867083 | 0.79 | RAB9A (0.50) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL554490 | 0.79 | RAB9A (0.59) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL5912481 | 0.78 | NPC1 (0.63) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL4644708 | 0.77 | NPC1 (0.57) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL11145110 | 0.77 | NPC1 (0.57) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL497521 | 0.77 | NPC1 (0.57) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL3247733 | 0.77 | NPC1 (0.57) | NPC1RAB9AALOX15HDAC3CA12 | |
| SCHEMBL289886 | 0.77 | NPC1 (0.57) | NPC1RAB9AALOX15HDAC3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | claimed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | claimed |
| EP-0500494-B1 | Surface modified pigment compositions | CIBA GEIGY AG (CH) | 1995-11-15 | — | — | EP | claimed |
| US-5256512-A | Gloss, image quality, durability | CANON KABUSHIKI KAISHA (JP) | 1993-10-26 | — | — | US | claimed |
| EP-0275636-B1 | COLOR TONER AND TWO-COMPONENT DEVELOPER CONTAINING SAME | CANON KABUSHIKI KAISHA (JP) | 1993-07-21 | — | — | EP | claimed |
| EP-0243304-B1 | SURFACE MODIFIED PIGMENT COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-06-02 | — | — | EP | claimed |
| US-5149610-A | Color toner and two-component developer containing same | CANON KABUSHIKI KAISHA (JP) | 1992-09-22 | — | — | US | claimed |
| US-5145524-A | With polymethyl vinyl ether; automotive and other finishes | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | claimed |
| JP-63170659-A | — | — | None | — | — | JP | disclosed |
| JP-63170657-A | — | — | None | — | — | JP | disclosed |
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | disclosed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-0990954-B1 | Resin-coated carrier, two component type developer, and developing method | CANON KK (JP) | 2007-01-24 | — | — | EP | disclosed |
| EP-1130065-B1 | Pigment compositions, production process thereof; colorants; and colored articles | DAINICHISEIKA COLOR CHEM (JP) | 2006-03-08 | — | — | EP | disclosed |
| EP-0332428-A2 | Image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4839255-A | IMPACTING MODIFIER TO BASE PARTICLES | CANON KABUSHIKI KAISHA (JP) | 1989-06-13 | — | — | US | disclosed |
| EP-0285140-A2 | Process for producing toner for developing electrostatic images | CANON KABUSHIKI KAISHA (JP) | 1988-10-05 | — | — | EP | disclosed |
| EP-0275636-A2 | Color toner and two-component developer containing same | CANON KABUSHIKI KAISHA (JP) | 1988-07-27 | — | — | EP | disclosed |
| JP-S63170657-A | TONER FOR ELECTRON PHOTOGRAPHY | CANON INC | 1988-07-14 | — | — | JP | disclosed |
| JP-S63170659-A | TONER FOR ELECTRON PHOTOGRAPHY | CANON INC | 1988-07-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | PPARG, PPARA, PPARD | NPC1 3730/4885RAB9A 3221/4885ALOX15 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.