Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155207 | 0.79 | NPC1 (0.57) | RAB9ANPC1TSHRHSD17B10HDAC3 | |
| SCHEMBL10841498 | 0.78 | TSHR (0.52) | RAB9ANPC1TSHRHSD17B10HDAC3 | |
| SCHEMBL10841553 | 0.77 | NPC1 (0.59) | RAB9ANPC1TSHRHSD17B10HDAC3 | |
| SCHEMBL6960400 | 0.76 | NPC1 (0.53) | RAB9ANPC1TSHRHSD17B10HDAC3 | |
| SCHEMBL289886 | 0.75 | NPC1 (0.57) | RAB9ANPC1TSHRHSD17B10HDAC3 | |
| SCHEMBL554490 | 0.73 | RAB9A (0.59) | RAB9ANPC1TSHRHSD17B10HDAC3 | |
| SCHEMBL727648 | 0.72 | RAB9A (0.53) | RAB9ANPC1HSD17B10HDAC3CA12 | |
| SCHEMBL4308659 | 0.72 | NPC1 (0.63) | RAB9ANPC1TSHRHSD17B10HDAC3 | |
| SCHEMBL5528005 | 0.72 | NFE2L2 (0.57) | RAB9ANPC1TSHRCA12CA1 | |
| SCHEMBL9659781 | 0.72 | NPC1 (0.53) | RAB9ANPC1TSHRHSD17B10HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149072-A1 | SULFONAMIDE HYDROXAMATES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037436-A1 | SULFONAMIDE HYDROXAMATES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-29 | — | — | WO | disclosed |