SCHEMBL5155355

SCHEMBL5155355

CCCCCCCCCCCCCCCC(=O)OCc1cnc(C)c(OC(=O)CCCCCCCCCCCCCCC)c1COC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
ELANE P08246 7/20 0.39
PAM P19021 2/20 0.38
P2RX7 Q99572 1/20 0.37
TSHR P16473 1/20 0.37
MAPT P10636 1/20 0.37
DNM1 Q05193 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
NR4A1 P22736 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31542572 0.93 TDP1 (0.41) DGKATDP1ELANEPAMP2RX7
SCHEMBL30886860 0.93 DGKA (0.36) DGKATDP1ELANEPAMMAPT
SCHEMBL668958 0.93 DGKA (0.36) DGKATDP1ELANEPAMMAPT
SCHEMBL20581979 0.90 TDP1 (0.38) TDP1TSHRMAPTALDH1A1
SCHEMBL483438 0.85 DGKA (0.43) DGKATDP1ELANEPAMP2RX7
SCHEMBL2905259 0.85 DGKA (0.43) DGKATDP1ELANEPAMP2RX7
SCHEMBL4971394 0.82 KDM4E (0.43) DGKAMAPTALDH1A1LMNA
SCHEMBL5153439 0.82 MAPT (0.39) MAPTALDH1A1
SCHEMBL9232006 0.81 KDM4E (0.51) DGKAELANEPAMALDH1A1LMNA
SCHEMBL516267 0.81 KDM4E (0.51) DGKAELANEPAMALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12396934-B2 Powder cosmetic JO COSMETICS CO., LTD. (JP) 2025-08-26 US disclosed
US-12383476-B2 W/O/W emulsion composition SHISEIDO COMPANY, LTD. (JP) 2025-08-12 US disclosed
CN-120131453-A W/O/W type emulsified composition 株式会社资生堂 2025-06-13 CN disclosed
WO-2025070287-A1 HAIR COSMETIC 日油株式会社 2025-04-03 WO disclosed
US-12151010-B2 Skin lightening agent POLA CHEMICAL INDUSTRIES, INC. (JP) 2024-11-26 US disclosed
US-12029303-B2 Method for preparation of a cosmetic kit SHISEIDO COMPANY, LTD. (JP) 2024-07-09 US disclosed
WO-2024142969-A1 WATER-IN-OIL EMULSION COMPOSITION 株式会社 資生堂 2024-07-04 WO disclosed
WO-2024142846-A1 COSMETIC COMPOSITION 株式会社 資生堂 2024-07-04 WO disclosed
WO-2024142892-A1 W/O/W EMULSIFIED COMPOSITION 株式会社 資生堂 2024-07-04 WO disclosed
WO-2024142843-A1 COSMETIC COMPOSITION 株式会社 資生堂 2024-07-04 WO disclosed
EP-1292266-B1 PYRIDOXINE AS NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES HENKEL KGAA (DE) 2005-11-16 EP disclosed
EP-1292263-B1 VITAMIN B6 DERIVATIVES AS PROTECTIVE COMPONENTS IN THE OXIDATIVE TREATMENT OF HAIR HENKEL KGAA (DE) 2005-11-02 EP disclosed
EP-1292265-A1 STRUCTURE-IMPROVING HAIR CARE AGENTS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP disclosed
EP-1292264-A2 AGENT FOR DYEING OR COLORING AND SIMULTANEOUSLY PROTECTING HAIR Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP disclosed
EP-1292266-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP disclosed
EP-1292263-A2 VITAMIN B6 DERIVATIVES AS PROTECTIVE COMPONENTS IN THE OXIDATIVE TREATMENT OF HAIR Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP disclosed
WO-2001097756-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed
WO-2001097760-A1 STRUCTURE-IMPROVING HAIR CARE AGENTS CONTAINING VITAMIN B6 AND DERIVATIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed
WO-2001097755-A2 VITAMIN B6 DERIVATIVES AS PROTECTIVE COMPONENTS IN THE OXIDATIVE TREATMENT OF HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed
WO-2001097757-A2 AGENT FOR DYEING OR COLORING AND SIMULTANEOUSLY PROTECTING HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12151010-B2 Skin lightening agent ACOX1, HAO1, CBR1 DGKA 4026/4885TDP1 4244/4885ELANE 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.