SCHEMBL483438

SCHEMBL483438

CCCCCCCC(=O)OCc1cnc(C)c(O)c1COC(=O)CCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.43
ELANE P08246 3/20 0.43
SGPL1 O95470 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
PAM P19021 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NR4A1 P22736 1/20 0.39
HDAC1 Q13547 1/20 0.39
P2RX7 Q99572 1/20 0.38
TSHR P16473 1/20 0.38
MAPT P10636 1/20 0.38
DEGS1 O15121 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905259 1.00 DGKA (0.43) DGKAELANESGPL1TDP1PAM
SCHEMBL9697296 0.94 DGKA (0.41) DGKAELANESGPL1TDP1ALDH1A1
SCHEMBL516267 0.93 KDM4E (0.51) DGKAELANESGPL1PAMKDM4E
SCHEMBL9232006 0.93 KDM4E (0.51) DGKAELANESGPL1PAMKDM4E
SCHEMBL31190161 0.86 ALDH1A1 (0.45) DGKAELANESGPL1TDP1KDM4E
SCHEMBL31208064 0.86 KDM4E (0.45) DGKAELANESGPL1KDM4EALDH1A1
SCHEMBL2423289 0.85 NR4A1 (0.43) DGKAELANETDP1PAMNR4A1
SCHEMBL5155355 0.85 DGKA (0.41) DGKAELANETDP1PAMALDH1A1
SCHEMBL21916175 0.84 PNPO (0.39) TDP1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL31746185 0.82 PNPO (0.40) SGPL1TDP1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 806 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858620-A Antimicrobial combinations 西姆莱斯有限公司 2024-04-09 CN claimed
CN-115957225-A MMP-1 expression inhibitor, skin external composition and application thereof 广东植肤生物科技有限公司 2023-04-14 CN claimed
CN-112022730-A Agent combination for skin care 西安博鸿生物技术有限公司 2020-12-04 CN claimed
CN-111904891-A Water-in-oil composition 西安博鸿生物技术有限公司 2020-11-10 CN claimed
EP-4122443-B1 COSMETIC COMPOSITION WITH SILICONE-MODIFIED POLYSACCHARIDE SHINETSU CHEMICAL CO (JP) 2026-05-06 EP disclosed
US-12611370-B2 Microemulsion composition and cosmetic containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-28 US disclosed
US-12600821-B2 Crosslinked organosilicon resin, a method for producing same, and a cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-14 US disclosed
EP-4717725-A1 ORGANOPOLYSILOXANE AND COSMETIC CONTAINING ORGANOPOLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-01 EP disclosed
EP-4714430-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-25 EP disclosed
EP-4706634-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-11 EP disclosed
EP-4706633-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-11 EP disclosed
EP-4702970-A1 COSMETIC CONTAINING AMINO ALCOHOL-MODIFIED SILICONE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-04 EP disclosed
EP-0450094-B1 HYDROPHILIC POLYMER-SILICATE MINERAL COMPOSITE AND ITS USE SHISEIDO CO LTD (JP) 1996-10-02 EP disclosed
US-5538728-A SKIN ULCER MEDICINE OF GELS OR COMPOSITES WITH POLYMER GELS AND LAXATIVES SHISEIDO COMPANY, LTD. (JP) 1996-07-23 US disclosed
EP-0688559-A1 Skin anti-ageing composition SHISEIDO COMPANY LIMITED (JP) 1995-12-27 EP disclosed
EP-0506961-B1 EXTERNAL PREPARATION FOR SKIN SHISEIDO CO LTD (JP) 1995-12-20 EP disclosed
US-5415875-A Applying hydrolyzed shell membrane and tocopherol derivative; aging and oxidation resistance SHISEIDO CO., LTD. (JP) 1995-05-16 US disclosed
EP-0601698-A1 Topical composition comprising tocopherol SHISEIDO COMPANY LIMITED (JP) 1994-06-15 EP disclosed
EP-0506961-A1 EXTERNAL PREPARATION FOR SKIN SHISEIDO COMPANY LIMITED (JP) 1992-10-07 EP disclosed
EP-0450094-A1 HYDROPHILIC POLYMER-SILICATE MINERAL COMPOSITE AND ITS USE SHISEIDO COMPANY LIMITED (JP) 1991-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611370-B2 Microemulsion composition and cosmetic containing the same MGLL, SGMS2, MAN2B1 DGKA 1331/4885ELANE 848/4885SGPL1 42/4885
US-12600821-B2 Crosslinked organosilicon resin, a method for producing same, and a cosmetic DEGS1, HACL2, GAR1 DGKA 870/4885ELANE 1163/4885SGPL1 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.