Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155455 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL9918688 | 0.76 | — | — | |
| SCHEMBL17249470 | 0.76 | — | — | |
| SCHEMBL9918687 | 0.75 | ALDH1A1 (0.32) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL14138306 | 0.73 | TRPA1 (0.31) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL14303933 | 0.66 | — | — | |
| SCHEMBL27541089 | 0.62 | — | — | |
| SCHEMBL11665315 | 0.61 | — | — | |
| SCHEMBL11094445 | 0.61 | ALDH1A1 (0.32) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL471236 | 0.61 | ALDH1A1 (0.32) | ALDH1A1TRPA1LMNAALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1262476-B1 | PROCESSES FOR PREPARING QUINOLINE DERIVATIVES AND INTERMEDIATES THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2007-01-10 | — | — | EP | disclosed |