Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575606 | 0.82 | — | — | |
| SCHEMBL5451213 | 0.82 | — | — | |
| SCHEMBL5554585 | 0.80 | NOS1 (0.31) | — | |
| SCHEMBL5554582 | 0.76 | — | — | |
| SCHEMBL5502631 | 0.72 | CYP1A2 (0.37) | KMT2AALDH1A1 | |
| SCHEMBL2526110 | 0.72 | HTT (0.41) | ALDH1A1 | |
| SCHEMBL8299815 | 0.71 | — | — | |
| SCHEMBL26718370 | 0.69 | CYP1A2 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL26064924 | 0.69 | — | — | |
| SCHEMBL16109535 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866277-A2 | SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | CELERA GENOMICS (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006102535-A2 | SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | CELERA GENOMICS (US) | 2006-09-28 | — | — | WO | disclosed |