Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451213 | 0.88 | — | — | |
| SCHEMBL13575606 | 0.88 | — | — | |
| SCHEMBL2482364 | 0.85 | CHRNA7 (0.38) | HTTOR51E2FKBP5CRBNNOS3 | |
| SCHEMBL2482486 | 0.82 | CYP1A2 (0.47) | HTTOR51E2FKBP5CRBNNOS1 | |
| SCHEMBL9766490 | 0.79 | CYP1A2 (0.49) | HTTL3MBTL1ALDH1A1CCR2 | |
| SCHEMBL5014640 | 0.78 | OR51E2 (0.37) | OR51E2FKBP5CRBN | |
| SCHEMBL6980000 | 0.76 | OR51E2 (0.34) | OR51E2FKBP5CRBNNOS3NOS1 | |
| SCHEMBL11260375 | 0.76 | POLB (0.46) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9779720 | 0.74 | OR51E2 (0.46) | HTTOR51E2FKBP5CRBNCTSD | |
| SCHEMBL28731850 | 0.74 | SIGMAR1 (0.40) | OR51E2FKBP5CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017012963-A1 | POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF | BASF SE (DE) | 2017-01-26 | — | — | WO | claimed |
| US-20080182773-A1 | Thickeners Based on Polymers Comprising Amine Groups | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-31 | — | — | US | claimed |
| EP-1572772-B1 | METHOD FOR PRODUCING POLYURETHANE PREPOLYMERS IN THE PRESENCE OF A CATALYST | HENKEL KGAA (DE) | 2006-09-06 | — | — | EP | claimed |
| US-20060004175-A1 | Method for producing a polyurethane prepolymer | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-01-05 | — | — | US | claimed |
| EP-1572772-A1 | METHOD FOR PRODUCING POLYURETHANE PREPOLYMERS IN THE PRESENCE OF A CATALYST | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-14 | — | — | EP | claimed |
| WO-2004055087-A1 | METHOD FOR PRODUCING POLYURETHANE PREPOLYMERS IN THE PRESENCE OF A CATALYST | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-01 | — | — | WO | claimed |
| US-10314841-B2 | Substituted pyrazoles as IRAK inhibitors | MERCK PATENT GMBH (DE) | 2019-06-11 | — | — | US | disclosed |
| EP-2170964-B1 | HIGH-CATION COPOLYMERS BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS | BASF SE (DE) | 2017-02-22 | — | — | EP | disclosed |
| WO-2017012963-A1 | POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF | BASF SE (DE) | 2017-01-26 | — | — | WO | disclosed |
| WO-2015106058-A1 | PYRIMIDINE PYRAZOLYL DERIVATIVES AND THEIR USE AS IRAK INHIBITORS | MERCK PATENT GMBH (DE) | 2015-07-16 | — | — | WO | disclosed |
| US-8623343-B2 | Highly cationic copolymers based on quaternized nitrogen-containing monomers | BASF SE (DE) | 2014-01-07 | — | — | US | disclosed |
| US-20130108959-A1 | USE OF A COMPOSITION COMPRISING VINYL MONOMER-COMPRISING POLYMER, SOLVENT AND AT LEAST ONE HALOGEN-FREE BIOCIDE | BASF SE (DE) | 2013-05-02 | — | — | US | disclosed |
| US-20120118446-A1 | AQUEOUS METAL QUENCHING MEDIUM | BASF SE (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-1999064426-A1 | HETEROBICYCLIC AND TRICYCLIC NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |
| US-4721768-A | Azetidinedione-monocarbonamide capped prepolymer | THE DOW CHEMICAL COMPANY (US) | 1988-01-26 | — | — | US | disclosed |
| US-4668756-A | POLYLACTAM BLOCK POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4604450-A | ANIONIC POLYMERIZATION OF LACTAMS; RIM; RING OPENING | THE DOW CHEMICAL COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0163954-A2 | Copolymers of lactams and azetidine-2,4-dione-based prepolymers | THE DOW CHEMICAL COMPANY (US) | 1985-12-11 | — | — | EP | disclosed |
| US-4550157-A | ANIONIC POLYMERIZATION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1985-10-29 | — | — | US | disclosed |
| US-4423204-A | HEAT RESISTANCE MOLDING MATERIALS | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10314841-B2 | Substituted pyrazoles as IRAK inhibitors | IRAK2, IRAK3, IRAK1 | HTT 4519/4885OR51E2 4168/4885FKBP5 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.