Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 12/20 | 1.00 |
| ▸ | PDE4A | P27815 | 15/20 | 0.85 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.85 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.85 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623455 | 0.92 | PDE4A (1.00) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL5400933 | 0.91 | PDE4A (0.91) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL3190853 | 0.89 | ADORA2B (0.92) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL21381238 | 0.88 | ADORA2B (0.86) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL21381263 | 0.88 | ADORA2B (1.00) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL5405285 | 0.88 | ADORA2A (0.86) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL7016029 | 0.87 | ADORA2A (1.00) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL21381261 | 0.87 | ADORA2B (0.89) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL5006812 | 0.87 | ADORA2B (0.92) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL21381255 | 0.85 | ADORA2B (0.92) | ADORA2AADORA2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150184166-A1 | CAFFEINE RESPONSIVE PROMOTERS AND REGULATORY GENES | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2015-07-02 | — | — | US | claimed |
| EP-2861740-A1 | CAFFEINE RESPONSIVE PROMOTERS AND REGULATORY GENES | University of Iowa Research Foundation (US) | 2015-04-22 | — | — | EP | claimed |
| WO-2013187957-A1 | CAFFEINE RESPONSIVE PROMOTERS AND REGULATORY GENES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-12-19 | — | — | WO | claimed |
| EP-2344126-A1 | METHOD FOR TREATMENT OF COPD AND OTHER PULMONARY DISEASES | Activaero GmbH (DE) | 2011-07-20 | — | — | EP | claimed |
| WO-2010043981-A1 | METHOD FOR TREATMENT OF COPD AND OTHER PULMONARY DISEASES | ACTIVAERO GMBH (DE) | 2010-04-22 | — | — | WO | claimed |
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | claimed |
| EP-0167566-A4 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | SUNSHINE ABRAHAM (US) | 1987-06-29 | — | — | EP | claimed |
| EP-0193599-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-09-10 | — | — | EP | claimed |
| EP-0165308-A4 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | RICHARDSON VICKS INC (US) | 1986-05-16 | — | — | EP | claimed |
| WO-1986001724-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-03-27 | — | — | WO | claimed |
| US-4567183-A | SYNERGISTIC, POTENTIATION | ANALGESIC ASSOCIATES (US) | 1986-01-28 | — | — | US | claimed |
| EP-0167566-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | SUNSHINE, Abraham (US) | 1986-01-15 | — | — | EP | claimed |
| EP-0165308-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | RICHARDSON VICKS INC (US) | 1985-12-27 | — | — | EP | claimed |
| US-4558051-A | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same | RICHARDSON-VICKS, INC. (US) | 1985-12-10 | — | — | US | claimed |
| WO-1985002540-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | RICHARDSON-VICKS, INC. (US) | 1985-06-20 | — | — | WO | claimed |
| WO-1985002542-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | SUNSHINE ABRAHAM | 1985-06-20 | — | — | WO | claimed |
| US-12559458-B2 | Co-crystals or salts of psilocin and methods of treatment therewith | Reset Pharmaceuticals, Inc. (US) | 2026-02-24 | — | — | US | disclosed |
| US-4207321-A | PROMOTES BLOOD PERFUSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559458-B2 | Co-crystals or salts of psilocin and methods of treatment therewith | SLC6A2, SLC6A4, SLC6A3 | ADORA2A 232/4885ADORA2B 1083/4885PDE4A 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.