Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4613529 | 1.00 | SCN9A (0.53) | SCN9AKMT2APADI4MAPTCYP19A1 | |
| SCHEMBL5149260 | 1.00 | SCN9A (0.53) | SCN9AKMT2APADI4MAPTCYP19A1 | |
| SCHEMBL5154580 | 0.86 | ICMT (0.55) | SCN9AKMT2AALDH1A1ICMT | |
| SCHEMBL5154481 | 0.84 | ICMT (0.62) | SCN9AICMT | |
| SCHEMBL5155704 | 0.84 | ICMT (0.62) | SCN9AICMT | |
| SCHEMBL5151526 | 0.83 | SCN9A (0.49) | SCN9AKMT2AMAPTALDH1A1RECQL | |
| SCHEMBL31236303 | 0.83 | KMT2A (0.69) | KMT2APADI4MAPTCYP19A1TBXAS1 | |
| SCHEMBL797161 | 0.83 | KMT2A (0.69) | KMT2APADI4MAPTCYP19A1TBXAS1 | |
| SCHEMBL5152025 | 0.82 | SCN9A (0.51) | SCN9AKMT2AMAPTALDH1A1RECQL | |
| SCHEMBL1661389 | 0.82 | GPR84 (0.57) | SCN9AMAPTALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | SCN9A 3913/4885KMT2A 916/4885PADI4 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.