SCHEMBL515618

SCHEMBL515618

c1ccc2c(c1)sc1c(-c3ccc(-c4nnc5c6ccccc6c6ccccc6n45)cc3)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.46
ALOX5 P09917 1/20 0.45
PARP14 Q460N5 1/20 0.38
PRKDC P78527 4/20 0.35
TYMS P04818 1/20 0.34
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
HPGD P15428 3/20 0.34
MAPT P10636 1/20 0.34
G6PD P11413 1/20 0.34
PKM P14618 1/20 0.34
ALOX12 P18054 1/20 0.34
HKDC1 Q2TB90 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPK9 P45984 1/20 0.33
MAPK14 Q16539 1/20 0.33
ADK P55263 1/20 0.33
HTT P42858 2/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10127327 0.99 POLB (0.46) POLBALOX5PARP14PRKDCTYMS
SCHEMBL10127328 0.95 POLB (0.45) POLBALOX5PARP14PRKDCTYMS
SCHEMBL10127329 0.92 POLB (0.47) POLBALOX5PARP14PRKDCTYMS
SCHEMBL515047 0.91 POLB (0.53) POLBALOX5PARP14PRKDCTYMS
SCHEMBL10127428 0.90 ALOX5 (0.42) POLBALOX5PARP14PRKDCALDH1A1
SCHEMBL10127459 0.90 POLB (0.43) POLBALOX5PARP14PRKDCTYMS
SCHEMBL10127332 0.90 POLB (0.43) POLBALOX5PARP14PRKDCMAPT
SCHEMBL10127316 0.90 POLB (0.43) POLBALOX5PARP14PRKDCMAPT
SCHEMBL10127378 0.90 POLB (0.51) POLBTYMSALDH1A1KDM4EHPGD
SCHEMBL10127331 0.90 POLB (0.52) POLBALOX5PARP14PRKDCTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230397494-A1 ORGANIC COMPOUND, CARRIER-TRANSPORT MATERIAL, HOST MATERIAL, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-12-07 US disclosed
CN-116568685-A Organic compound, carrier transporting material, host material, light-emitting device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2023-08-08 CN disclosed
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 US disclosed
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 US disclosed
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 US disclosed
WO-2012017842-A1 TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 WO disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 US disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 US disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230397494-A1 ORGANIC COMPOUND, CARRIER-TRANSPORT MATERIAL, HOST MATERIAL, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SLC43A1, SLCO4C1, DDT POLB 3941/4885ALOX5 3476/4885PARP14 3086/4885
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device HTR3D, KCNQ4, KCNQ3 POLB 3317/4885ALOX5 1457/4885PARP14 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.