SCHEMBL5157148

SCHEMBL5157148

O=C1CC(c2cccc(N3C(=O)C=CC3=O)c2)C(=O)N1O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MGLL Q99685 10/20 0.49
FAAH O00519 4/20 0.49
HSP90AA1 P07900 3/20 0.43
PKM P14618 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.42
HPN P05981 1/20 0.39
TSHR P16473 1/20 0.38
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229803 0.77 MGLL (0.47) KMT2AMEN1SMN1; SMN2L3MBTL1MGLL
SCHEMBL20595265 0.77 KMT2A (0.43) KMT2AMEN1SMN1; SMN2L3MBTL1PKM
SCHEMBL30073628 0.77 KMT2A (0.43) KMT2AMEN1SMN1; SMN2L3MBTL1PKM
SCHEMBL2924606 0.75 KMT2A (0.62) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL5501312 0.75 ALDH1A1 (0.51) KMT2AMEN1SMN1; SMN2L3MBTL1MGLL
SCHEMBL31022582 0.72 GAA (0.44) KMT2AMEN1SMN1; SMN2L3MBTL1MGLL
SCHEMBL29448213 0.72 MGLL (0.47) KMT2AMEN1SMN1; SMN2L3MBTL1MGLL
SCHEMBL30515182 0.72 KMT2A (0.46) KMT2AMEN1SMN1; SMN2L3MBTL1MGLL
SCHEMBL29448212 0.72 MGLL (0.47) KMT2AMEN1SMN1; SMN2L3MBTL1MGLL
SCHEMBL29189760 0.72 MGLL (0.47) KMT2AMEN1SMN1; SMN2L3MBTL1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0942996-B1 THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY DIATIDE INC (US) 2007-01-03 EP claimed
CN-110945086-B Coating for removing aldehydes and preparation method thereof 陶氏环球技术有限责任公司 2022-09-16 CN disclosed