SCHEMBL5157329

SCHEMBL5157329

Cc1cc(Sc2cc(C)c(O)cc2C(C)(C)CC(C)(C)C)c(C(C)(C)CC(C)(C)C)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.43
ALDH1A1 P00352 4/20 0.43
CYP3A4 P08684 4/20 0.43
HIF1A Q16665 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 2/20 0.43
MAPK1 P28482 2/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SHBG P04278 1/20 0.35
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP1A2 P05177 2/20 0.33
ATP2A2 P16615 1/20 0.33
ATP2A3 Q93084 1/20 0.33
ESR1 P03372 5/20 0.33
ESR2 Q92731 3/20 0.33
AR P10275 2/20 0.33
HSD17B10 Q99714 3/20 0.32
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127401 0.82 ALOX15 (0.43) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL5157322 0.81 CNR1 (0.43) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL9008194 0.80 ALOX15 (0.60) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL2481099 0.79 ALOX15 (0.66) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL9745046 0.79 ALOX15 (0.56) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL28612138 0.76 SHBG (0.41) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL126587 0.75 ALOX15 (0.52) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL3821355 0.72 SMN1; SMN2 (0.42) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL29043370 0.72 CYP3A4 (0.41) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2
SCHEMBL9311748 0.71 ALOX15 (0.48) ALOX15ALDH1A1CYP3A4HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4518977-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-05-21 US claimed
US-11524514-B2 Tamper-proof medium for thermal printing OMYA INTERNATIONAL AG (CH) 2022-12-13 US disclosed
CN-110799345-B Tamper-resistant media for thermal printing 欧米亚国际集团 2022-04-19 CN disclosed
EP-3642044-B1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING OMYA INT AG (CH) 2021-07-28 EP disclosed
US-20200198386-A1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING OMYA INTERNATIONAL AG (CH) 2020-06-25 US disclosed
EP-3642044-A1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING Omya International AG (CH) 2020-04-29 EP disclosed
EP-3418064-A1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING Omya International AG (CH) 2018-12-26 EP disclosed
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-1448397-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2007-07-11 EP disclosed
US-7232791-B2 Two or more kinds of colorless or pale colored dye precursors (e.g., phthalein dye) are contained in complex fine particles of a polymer of a multivalence isocyanate compound and furthers contain 4,4'-diisocyanate-3,3'-dimethyl-1,1'-biphenyl and/or polymethylenepolyphenylene polyisocyanate. NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 2007-06-19 US disclosed
EP-0289041-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-11-02 EP disclosed
EP-0154336-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1988-10-26 EP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
US-4628336-A POLYPHENYL ESTERS; SOIL RESISTANCE; IMAGE STABILITY JUJO PAPER CO., LTD. (JP) 1986-12-09 US disclosed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP disclosed
US-4590499-A MONOBENZYL CALCIUM PHTHALATE OR ZINC P-NITROBENZOATE AS STABILIZER IN THE CHROMOGEN LAYER; OIL REPELLENTS JUJO PAPER CO., LTD. (JP) 1986-05-20 US disclosed
US-4573062-A HYDROXYBENZ/YLOXYBENZOIC ACID COLOR DEVELOPER AND LEUCO DYE JUJO PAPER CO., LTD. (JP) 1986-02-25 US disclosed
EP-0168819-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-01-22 EP disclosed
EP-0154336-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-09-11 EP disclosed
US-4518977-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-05-21 US disclosed