Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160107 | 0.97 | KMT2A (0.42) | KMT2AGAAHSD17B10ATMCYP24A1 | |
| SCHEMBL20810547 | 0.87 | SMN1; SMN2 (0.40) | KMT2AGAAHSD17B10NAMPTHDAC3 | |
| SCHEMBL5157915 | 0.86 | GAA (0.44) | KMT2AGAAHSD17B10ATMCYP24A1 | |
| SCHEMBL20810506 | 0.85 | ASAH2 (0.36) | KMT2AGAAHSD17B10ATMHDAC3 | |
| SCHEMBL16799902 | 0.85 | SMN1; SMN2 (0.41) | KMT2AHSD17B10HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL16799903 | 0.85 | SMN1; SMN2 (0.41) | KMT2AHSD17B10HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL17977261 | 0.85 | SMN1; SMN2 (0.41) | KMT2AHSD17B10HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL5159515 | 0.84 | SMPD1 (0.48) | KMT2AGAAHSD17B10ATMCYP24A1 | |
| SCHEMBL2623654 | 0.84 | SMN1; SMN2 (0.40) | KMT2ANAMPTHDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL16799707 | 0.84 | LMNA (0.42) | KMT2ANAMPTHDAC3HDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |