Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157580 | 0.87 | GAA (0.46) | SMPD1GAAKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL5160107 | 0.86 | KMT2A (0.42) | SMPD1GAAKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL5157915 | 0.85 | GAA (0.44) | SMPD1GAAKMT2AHSD17B10ATM | |
| SCHEMBL5157370 | 0.84 | KMT2A (0.43) | SMPD1GAAKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL20810480 | 0.83 | SMN1; SMN2 (0.55) | SMPD1KMT2ASMN1; SMN2NAAAL3MBTL1 | |
| SCHEMBL9508117 | 0.83 | HDAC1 (0.56) | SMPD1SMN1; SMN2 | |
| SCHEMBL20810490 | 0.83 | SMN1; SMN2 (0.52) | GAAKMT2AHSD17B10SMN1; SMN2NAMPT | |
| SCHEMBL9508113 | 0.83 | HDAC1 (0.56) | SMPD1SMN1; SMN2 | |
| SCHEMBL13302517 | 0.81 | CNR2 (0.48) | SMN1; SMN2ASAH2ATM | |
| SCHEMBL2764163 | 0.81 | CNR2 (0.48) | SMN1; SMN2ASAH2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |