SCHEMBL5157425

SCHEMBL5157425

CC(COc1c(Cl)cc(Cl)cc1Cl)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
KDM4E B2RXH2 2/20 0.40
SCN4A P35499 2/20 0.39
PLAU P00749 1/20 0.39
TDP1 Q9NUW8 3/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
AHR P35869 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
STING1 Q86WV6 2/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5800647 0.83 KMT2A (0.56) KDM4ELMNAALDH1A1KMT2A
SCHEMBL5162157 0.79 TDP1 (0.59) TSHRTDP1MRGPRX4SMN1; SMN2LMNA
SCHEMBL5159185 0.78 GABRR1 (0.34) STING1
SCHEMBL5157810 0.76 TDP1 (0.56) TSHRTDP1SMN1; SMN2STING1LMNA
SCHEMBL8606655 0.74 SCN4A (0.48) TSHRSCN4ATDP1LMNAMAPT
SCHEMBL28619870 0.74 PPARA (0.58) SCN4AALDH1A1KMT2A
SCHEMBL21895800 0.74 PPARA (0.58) SCN4AALDH1A1KMT2A
SCHEMBL1305299 0.74 PPARA (0.58) SCN4AALDH1A1KMT2A
SCHEMBL7433742 0.73 TSHR (0.51) TSHRKDM4ETDP1SMN1; SMN2ALDH1A1
Water SCHEMBL11798405 0.72 PPARA (0.56) SCN4AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP claimed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US claimed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP claimed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO claimed
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP disclosed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP disclosed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO disclosed