SCHEMBL5162157

SCHEMBL5162157

CC(COc1ccc(Cl)cc1Cl)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
TSHR P16473 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
LMNA P02545 1/20 0.54
HPGD P15428 1/20 0.53
NLRP1 Q9C000 1/20 0.53
RECQL P46063 1/20 0.52
MRGPRX4 Q96LA9 5/20 0.51
MAPT P10636 1/20 0.51
FFAR1 O14842 1/20 0.49
PPARA Q07869 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8107213 0.86 FFAR1 (0.62) TDP1TSHRSMN1; SMN2LMNAHPGD
SCHEMBL5157810 0.82 TDP1 (0.56) TDP1TSHRSMN1; SMN2LMNAMAPT
SCHEMBL5159157 0.81 MEN1 (0.54) TDP1TSHRSMN1; SMN2HPGD
SCHEMBL21895849 0.81 MEN1 (0.54) TDP1TSHRSMN1; SMN2HPGD
SCHEMBL11595834 0.80 CYP1A2 (0.56) TDP1TSHRSMN1; SMN2LMNAHPGD
SCHEMBL9967704 0.80 KDM1A (0.56) TDP1TSHRSMN1; SMN2LMNAHPGD
SCHEMBL5157425 0.79 TSHR (0.43) TDP1TSHRSMN1; SMN2LMNAMRGPRX4
SCHEMBL11592951 0.78 LMNA (0.57) TDP1TSHRSMN1; SMN2LMNAHPGD
2,4-Dichlorophenoxyacetic Acid SCHEMBL29010269 0.77 TDP1 (0.82) TDP1TSHRSMN1; SMN2LMNARECQL
2,4-Dichlorophenoxyacetic Acid SCHEMBL29010254 0.77 TDP1 (0.82) TDP1TSHRSMN1; SMN2LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP claimed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US claimed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP claimed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO claimed
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP disclosed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US disclosed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP disclosed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO disclosed