Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501814 | 0.90 | TSHR (0.58) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL2557590 | 0.85 | ERN1 (0.45) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL2557044 | 0.82 | TSHR (0.43) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL9780698 | 0.81 | KMT2A (0.49) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL9780706 | 0.81 | KMT2A (0.49) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL7788712 | 0.79 | KMT2A (0.44) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL7788714 | 0.79 | KMT2A (0.44) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL9780822 | 0.78 | TDP1 (0.55) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL1360515 | 0.78 | TDP1 (0.55) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| (S)-Dichlorprop SCHEMBL1535831 | 0.77 | TSHR (0.73) | TSHRHTR2AHTR2CHTR2BPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155010-A1 | ACETAMIDO ACETONITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND/OR CATHEPSIN S | AstraZeneca AB (SE) | 2001-11-21 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000049007-A1 | ACETAMIDO ACETONITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND/OR CATHEPSIN S | ASTRAZENECA AB (SE) | 2000-08-24 | — | — | WO | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4672065-A | TOMATO LATE BLIGHT | CHEVRON RESEARCH COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4535087-A | FOR TOMATO LATE BLIGHT | CHEVRON RESEARCH COMPANY (US) | 1985-08-13 | — | — | US | disclosed |