SCHEMBL515767

SCHEMBL515767

Cn1c(=O)c2[nH]c(-c3ccc(Cl)c(Cl)c3)nc2n(C)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.70
ALDH1A1 P00352 1/20 0.70
HPGD P15428 1/20 0.70
ADORA2B P29275 3/20 0.66
ADORA2A P29274 2/20 0.66
CYP1A2 P05177 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
ADORA1 P30542 1/20 0.65
BLM P54132 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
HSD17B10 Q99714 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25090501 0.89 ADORA2A (0.69) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL515588 0.85 KDM4E (0.76) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL25090450 0.82 ADORA2A (0.66) KDM4EADORA2BADORA2ACYP1A2ADORA3
SCHEMBL25090657 0.82 ADORA2B (0.73) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL25089912 0.82 ADORA2A (0.74) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL516013 0.81 ADORA2B (0.77) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL25090423 0.81 ALDH1A1 (0.65) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL516029 0.80 ADORA2B (0.75) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL10723936 0.80 ADORA2B (1.00) KDM4EALDH1A1HPGDADORA2BADORA2A
SCHEMBL25090491 0.80 ADORA2B (0.75) KDM4EALDH1A1HPGDADORA2BADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250386846-A1 Food Compositions Including Aragonite NANT HOLDINGS IP LLC (US) 2025-12-25 US disclosed
US-12419336-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2025-09-23 US disclosed
US-20250194654-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2025-06-19 US disclosed
US-12310392-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2025-05-27 US disclosed
US-20240381918-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2024-11-21 US disclosed
US-12089621-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2024-09-17 US disclosed
US-20230354865-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2023-11-09 US disclosed
US-11793224-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2023-10-24 US disclosed
US-20230085907-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2023-03-23 US disclosed
US-11533940-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2022-12-27 US disclosed
WO-1996029997-A1 SOFT GELATIN CAPSULE WITH A GELATIN SHELL COMPRISING XANTHINE DERIVATIVE THE PROCTER & GAMBLE COMPANY (US) 1996-10-03 WO disclosed
EP-0165308-B1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME Richardson-Vicks, Inc. (US) 1989-03-22 EP disclosed
EP-0167566-A4 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. SUNSHINE ABRAHAM (US) 1987-06-29 EP disclosed
EP-0165308-A4 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. RICHARDSON VICKS INC (US) 1986-05-16 EP disclosed
US-4567183-A SYNERGISTIC, POTENTIATION ANALGESIC ASSOCIATES (US) 1986-01-28 US disclosed
EP-0167566-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE, Abraham (US) 1986-01-15 EP disclosed
EP-0165308-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. RICHARDSON VICKS INC (US) 1985-12-27 EP disclosed
US-4558051-A Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same RICHARDSON-VICKS, INC. (US) 1985-12-10 US disclosed
WO-1985002540-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME RICHARDSON-VICKS, INC. (US) 1985-06-20 WO disclosed
WO-1985002542-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE ABRAHAM 1985-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250386846-A1 Food Compositions Including Aragonite PLCG2, PLCG1, PLCB3 KDM4E 4328/4885ALDH1A1 4338/4885HPGD 3617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.