SCHEMBL5157739

SCHEMBL5157739

Cc1nc[nH]c1CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1509606 0.82
SCHEMBL12844533 0.82
Hydrochloric Acid SCHEMBL1636691 0.80
4-Methylhistamine SCHEMBL11452941 0.78
SCHEMBL6850308 0.77 HRH3 (0.42)
SCHEMBL1311876 0.76 HSD17B10 (0.44)
SCHEMBL3318202 0.76 HRH2 (0.36)
SCHEMBL19938003 0.75 NUDT1 (0.36)
SCHEMBL1311858 0.75 CYP2C19 (0.36)
SCHEMBL11035051 0.75 L3MBTL1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1298305-A Interleukin-6 production inhibitors TORAY INDUSTRIES (JP) 2001-06-06 CN claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
EP-1472232-B1 PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF YUHAN CORP (KR) 2007-01-24 EP disclosed
EP-1472232-B1 PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF YUHAN CORP (KR) 2007-01-24 EP disclosed
EP-1472232-A4 PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF YUHAN CORP (KR) 2006-02-01 EP disclosed
CN-1217666-C Interleukin-6 production inhibitors TORAY INDUSTRIES (JP) 2005-09-07 CN disclosed
EP-1472232-A1 PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF Yuhan Corporation (KR) 2004-11-03 EP disclosed
US-6706888-B2 REACTING A 3-HALOTETRAHYDROFURAN OR TETRAHYDROPYRAN COMPOUND WITH FORMAMIDINE OR ITS SALT IN THE PRESENCE OF A BASE TO PRODUCE A 3-(1H-IMIDAZOL-4-YL)PROPANOL DERIVATIVE; EFFICIENCY; INTERMEDIATES; ANTICARCINOGENIC AGENTS; VIRICIDES; YUHAN CORPORATION (KR) 2004-03-16 US disclosed
US-20030153769-A1 Processes for preparing imidazole derivatives and salts thereof YUHAN CORPORATION 2003-08-14 US disclosed
WO-2003066600-A1 PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF YUHAN CORPORATION (KR) 2003-08-14 WO disclosed
CN-1298305-A Interleukin-6 production inhibitors TORAY INDUSTRIES (JP) 2001-06-06 CN disclosed
EP-0473626-B1 NEW DIPHOSPHONIC ACID DERIVATIVES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM BOEHRINGER MANNHEIM GMBH (DE) 1993-12-01 EP disclosed
US-5206253-A DISPHOSPHONIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM, GMBH (DE) 1993-04-27 US disclosed
EP-0473626-A1 NEW DIPHOSPHONIC ACID DERIVATIVES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM. BOEHRINGER MANNHEIM GMBH (DE) 1992-03-11 EP disclosed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US disclosed