SCHEMBL5157997

SCHEMBL5157997

C1CNCC(CN2CCOCC2)[N]1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2289712 0.84 CXCR4 (0.31)
SCHEMBL11555193 0.84 CHRM5 (0.33)
SCHEMBL945963 0.83 KEAP1 (0.38) GAAALDH1A1
SCHEMBL945748 0.82 CHRM5 (0.36)
SCHEMBL5488980 0.75 CHRM5 (0.32)
SCHEMBL950032 0.73 CXCR4 (0.40) GAAALDH1A1
SCHEMBL713471 0.73 L3MBTL1 (0.40) GAAALDH1A1
SCHEMBL665254 0.73 GAA (0.36) GAAALDH1A1
SCHEMBL666969 0.73 GAA (0.36) GAAALDH1A1
SCHEMBL667835 0.73 GAA (0.36) GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1740155-A1 POLYCYLIC THIAZOLES AS POTASSIUM ION CHANNEL MODULATORS Icagen, Inc. (US) 2007-01-10 EP disclosed
WO-2005099673-A1 POLYCYLIC THIAZOLES AS POTASSIUM ION CHANNEL MODULATORS ICAGEN, INC. (US) 2005-10-27 WO disclosed