SCHEMBL51580

SCHEMBL51580

CCOc1cc(OC(CC)Oc2ccc(S(=O)(=O)c3ccc(O)cc3)cc2)ccc1S(=O)(=O)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.42
ELANE P08246 2/20 0.41
GAA P10253 2/20 0.40
PKM P14618 1/20 0.40
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.37
MMP2 P08253 2/20 0.35
MMP9 P14780 2/20 0.35
MMP8 P22894 2/20 0.35
MMP14 P50281 2/20 0.35
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35
MMP16 P51512 1/20 0.35
CTRC Q99895 1/20 0.35
NAMPT P43490 1/20 0.35
CNR1 P21554 2/20 0.34
CNR2 P34972 1/20 0.34
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64386 0.92 LTA4H (0.40) LTA4HELANEGAAPKMNPSR1
SCHEMBL51702 0.89 LTA4H (0.50) LTA4HELANEGAAPKMNPSR1
SCHEMBL1395586 0.81 LTA4H (0.46) LTA4HELANEGAAPKMNPSR1
SCHEMBL50955 0.81 PKM (0.59) ELANEGAAPKMNPSR1MMP2
SCHEMBL10716234 0.78 GAA (0.44) LTA4HELANEGAAPKMRXFP1
SCHEMBL51006 0.75 PKM (0.51) ELANEGAAPKMNPSR1MMP13
SCHEMBL1396158 0.75 LTA4H (0.48) LTA4HELANEGAAPKMNPSR1
SCHEMBL51737 0.74 GAA (0.48) LTA4HELANEGAAPKMNPSR1
SCHEMBL7055484 0.71 GAA (0.39) ELANEGAAPKMNPSR1RXFP1
SCHEMBL417833 0.71 GAA (0.65) LTA4HELANEGAAPKMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475095-B1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH CO LTD (JP) 2020-01-22 EP disclosed
EP-3475095-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE Ricoh Company, Ltd. (JP) 2019-05-01 EP disclosed
EP-2484534-B1 RECORDING MATERIAL USING PHENOLIC COMPOUND NIPPON SODA CO (JP) 2019-01-16 EP disclosed
EP-1930318-B1 Process for producing diphenyl sulfone compound NIPPON SODA CO (JP) 2017-03-08 EP disclosed
EP-2289704-B1 COLOR-DEVELOPING COMPOSITION AND RECORDING MATERIAL CONTAINING THE SAME NIPPON SODA CO (JP) 2014-05-14 EP disclosed
US-8722576-B2 Thermosensitive recording label NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-05-13 US disclosed
EP-2474963-B1 THERMOSENSITIVE RECORDING LABEL JUJO PAPER CO LTD (JP) 2013-11-13 EP disclosed
US-8551911-B2 Recording material using phenolic compound NIPPON SODA CO., LTD. (JP) 2013-10-08 US disclosed
US-8546299-B2 Color-developing composition and recording material containing the same NIPPON SODA CO., LTD. (JP) 2013-10-01 US disclosed
EP-1273570-B1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO (JP) 2013-07-17 EP disclosed
EP-0999072-B1 A thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2003-05-02 EP disclosed
EP-1273570-A1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO., LTD. (JP) 2003-01-08 EP disclosed
US-6407036-B1 MIXTURE OF FATTY AMIDE AND DIPHENYL SULFONE COMPOUND NIPPON PAPER INDUSTRIES CO. LTD (JP) 2002-06-18 US disclosed
EP-0860429-B1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO (JP) 2001-12-12 EP disclosed
US-6303540-B1 CONTAINING DIPHENYLSULFONE BRIDGEABLE TYPE COMPOUND AND SULFONAMIDE COMPOUND NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-10-16 US disclosed
EP-1092551-A2 Multi chromatic thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-1092552-A1 THERMAL RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-0999072-A1 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-05-10 EP disclosed
US-6037308-A HIGH RECORDED IMAGE PRESERVABILITY NIPPON SODA CO., LTD. (JP) 2000-03-14 US disclosed
EP-0860429-A1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO., LTD. (JP) 1998-08-26 EP disclosed